Results 41 to 50 of about 132,025 (234)
A team science approach to discover novel targets for infantile spasms (IS)
Epilepsia Open, 2021 Infantile spasms (IS) is a devastating epilepsy syndrome that typically begins in the first year of life. Symptoms consist of stereotypical spasms, developmental delay, and electroencephalogram (EEG) that may demonstrate Hypsarhythmia.
The CURE Infantile Spasms Consortium, CURE Staff +2 more
doaj +1 more source
The early electroclinical manifestations of infantile spasms: A video EEG study
Annals of Indian Academy of Neurology, 2016 Purpose: Infantile spasms are described as flexor extensor and mixed; but more features of their semiology and ictal electroencephalography (EEG) changes are sparse in the literature.
Mary Iype +4 more
doaj +1 more source
Limited efficacy of zonisamide in the treatment of refractory infantile spasms
Epilepsia Open, 2020 A series of relatively small studies collectively suggest that zonisamide may be effective in the treatment of infantile spasms. Using a large single‐center cohort of children with infantile spasms, we set out to evaluate the efficacy and safety of ...
Shaun A. Hussain +7 more
doaj +1 more source
Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms
Clinical Neurophysiology, 2020 Objective To investigate the diagnostic utility of high frequency oscillations (HFOs) via scalp electroencephalogram (EEG) in infantile spasms. Methods We retrospectively analyzed interictal slow-wave sleep EEGs sampled at 2,000 Hz recorded from 30 ...
H. Nariai +12 more
semanticscholar +1 more source
BMC Pediatrics, 2010 Background Infantile spasms represent a serious epileptic syndrome that occurs in the early infantile age. ACTH and Vigabatrin are actively investigated drugs in its treatment.
Ishaque Sidra +3 more
doaj +1 more source
Management of Infantile Spasms During the COVID-19 Pandemic
Journal of Child Neurology, 2020 Circumstances of the COVID-19 pandemic have mandated a change to standard management of infantile spasms. On April 6, 2020, the Child Neurology Society issued an online statement of immediate recommendations to streamline diagnosis and treatment of ...
Z. Grinspan +24 more
semanticscholar +1 more source
Developmental Medicine & Child Neurology, 2020 To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized controlled trials (RCTs).
Shaojun Li +4 more
semanticscholar +1 more source
Risk for infantile spasms after acute symptomatic neonatal seizures
Epilepsia, 2020 Infantile spasms (IS) is a severe epilepsy in early childhood. Early treatment of IS provides the best chance of seizure remission and favorable developmental outcome.
Hannah C. Glass +11 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2022 Recurrent and profound hypoglycemia is a leading cause of neonatal brain injury. Small-for-gestational-age infants are at risk of hypoglycemia due to substrate deficiency and hyperinsulinism. Inappropriate insulin secretion by the β-cells of the pancreas
Suresh Chandran +11 more
doaj +1 more source
Short Course and Early Switch of Vigabatrin for Infantile spasms [PDF]
Annals of Child Neurology, 2020 Purpose Vigabatrin has proven efficacy in the treatment of infantile spasms, but it carries the risk of irreversible visual field constriction. The incidence of vigabatrin-induced visual field constriction seems to depend on the extent of vigabatrin ...
Hye Won Ryu +6 more
doaj +1 more source