Results 81 to 90 of about 51,683 (162)

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

BRAIN TUMORS AND INFANTILE SPASMS

open access: yes, 1995
Two patients, aged 6 and 7 months, with brain tumors who presented with infantile spasms and hypsarrhythmia are reported from Sapporo and Asahikawa Medical Universities ...
J Gordon Millichap
core   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Infantile Spasms in Children with Down Syndrome [PDF]

open access: yes, 2011
Down syndrome (DS) is the most common genetic cause of mental retardation. It is estimated that 5–13% of persons affected by DS have seizures. Infantile spasms are the most common type of seizures and usually are well controlled with steroids and ...
Lucija Lujić   +9 more
core   +1 more source

Methysergide and Infantile Spasms

open access: yesPediatric Neurology Briefs, 1989
A trial of antiadrenergic and antiseretonergic drugs in the treatment of 24 newly diagnosed and previously untreated infantile spasm patients is reported from the Epilepsy Research Center, Section of Neurophysiology, Department of Neurology, Baylor ...
J Gordon Millichap
doaj   +1 more source

Infantile Spasms and NF-1

open access: yes, 1994
Two patients, ages 7 and 2 years, with neurofibromatosis type 1 complicated by infantile spasms are reported from the Pediatric Institutes, Siena and Catania ...
J Gordon Millichap
core   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

Infantile Spasms and ACTH Dosage

open access: yes, 1987
Results of corticotropin treatment of 33 patients with infantile spasms are reported from the Instituto Clinica Pediatrica, Universita di Siena ...
J Gordon Millichap
core   +1 more source

Cerebrospinal fluid corticotropin and cortisol are reduced in infantile spasms [PDF]

open access: yes, 1995
Infantile spasms respond to ACTH, and levels of the hormone in cerebrospinal fluid of untreated infants with this disorder were found to be lower than in age-matched controls. In this study we analyzed cerebrospinal fluid cortisol and ACTH using improved
O. Carter Snead   +9 more
core   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

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