Results 91 to 100 of about 121,621 (353)

Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography–High‐Resolution Mass Spectrometry (GC‐HRMS) and Liquid Chromatography–High‐Resolution Tandem Mass Spectrometry (LC‐HRMS/MS)

open access: yesDrug Testing and Analysis, EarlyView.
This study developed a comprehensive metabolomics workflow using GC‐HRMS and LC‐HRMS/MS and analyzed 35 CBD‐type cannabis flowers grown under varying conditions. Key discriminative compounds enabled classification by chemical phenotype and cultivation environment. The results showed that environmental factors influence chemical profiles, supporting the
Sandra N. Poetzsch   +3 more
wiley   +1 more source

Necrotizing enterocolitis totalis complicates an infantile presentation of ARL6IP1-related spastic paraplegia 61

open access: yesJournal of Pediatric Surgery Case Reports, 2021
Spastic paraplegia 61 is a rare, complicated form of hereditary spastic paraplegia characterized by diffuse sensory and motor polyneuropathy. Knowledge about the clinical manifestations of disease in patients with this genetic condition is limited.
E.K. Ninmer   +3 more
doaj  

Long-term functional benefits of selective dorsal rhizotomy for spastic cerebral palsy.

open access: yesJournal of Neurosurgery: Pediatrics, 2013
OBJECT Large-scale natural history studies of gross motor development have shown that children with spastic cerebral palsy (CP) plateau during childhood and actually decline through adolescence.
R. Dudley   +10 more
semanticscholar   +1 more source

Rest‐activity rhythm phenotypes in adults with epilepsy and intellectual disability

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Rest‐activity rhythms (RARs) are perturbed in many forms of neuropsychiatric illness. In this study, we applied wrist actigraphy to describe RAR perturbations in intellectually disabled adults with epilepsy (“E + ID”), using a cross‐sectional case–control design.
Nandani Adhyapak   +3 more
wiley   +1 more source

A pseudo‐homozygous missense variant and Alu‐mediated exon 5 deletion in FARS2 causing spastic paraplegia 77

open access: yesAnnals of Clinical and Translational Neurology
FARS2‐associated hereditary spastic paraplegia, later onset spastic paraplegia type 77, is a rarely neurodegenerative disease. Here, we reported two affected siblings in an autosomal recessive spastic paraplegia family with a pseudo‐homozygous missense ...
Shu‐Huai Lin   +7 more
doaj   +1 more source

Hereditary spastic paraplegias

open access: yesНервно-мышечные болезни
Hereditary spastic paraplegias represent a group of hereditary neurodegenerative disorders predominantly affecting corticospinal tracts which manifest with prominent spasticity and reduced power in the muscles of the lower limbs.
R. F. Kutlubaeva   +4 more
doaj   +1 more source

Algorithm of surgical treatment of pain and spastic syndromes in patients after spinal cord injury [PDF]

open access: yesСаратовский научно-медицинский журнал, 2015
Objective: to develop an algorithm for surgical treatment of pain and spasticity in patients with consequences of spinal cord injury. Materials and Methods.
Ninel V.G.   +3 more
doaj  

A spastic paraplegia mouse model reveals REEP1-dependent ER shaping.

open access: yesJournal of Clinical Investigation, 2013
Axonopathies are a group of clinically diverse disorders characterized by the progressive degeneration of the axons of specific neurons. In hereditary spastic paraplegia (HSP), the axons of cortical motor neurons degenerate and cause a spastic movement ...
C. Beetz   +19 more
semanticscholar   +1 more source

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