Results 101 to 110 of about 121,621 (353)

Is highly purified cannabidiol a treatment opportunity for drug‐resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?

open access: yesEpilepsia Open, EarlyView.
Abstract Objective This study aimed to evaluate the efficacy and safety of adjunctive, highly purified Cannabidiol (Epidiolex®) in individuals with drug‐resistant epilepsy (DRE) due to genetically determined typical Rett Syndrome (RTT) and CDKL5 Deficiency Disorder (CDD). Methods We recruited subjects with genetically confirmed typical RTT and CDD with
Aglaia Vignoli   +22 more
wiley   +1 more source

Phytochemical Contents and Bioactive Compounds in Widely Consumed Cereals, Legumes, and Vegetables in Abruzzo Region, Italy: A Critical Review

open access: yesFood Safety and Health, EarlyView.
This review aims to collect and identify cereals, legumes, and vegetables mostly consumed in the Abruzzo region from 2020 till now, pointing attention to their biological effects. ABSTRACT The Abruzzo region boasts a wide range of typical food products including cereals, legumes, and vegetables. In this context, they take part in the Mediterranean diet,
Giulia Gentile   +3 more
wiley   +1 more source

The novel de novo mutation of KIF1A gene as the cause for Spastic paraplegia 30 in a Japanese case

open access: yeseNeurologicalSci, 2019
Spastic paraplegia 30 is a recently established autosomal recessive disease characterized by a complex form of spastic paraplegia associated with neuropathy.
Keisuke Yoshikawa   +11 more
doaj  

The end of spasticity? [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2017
Video Podcast: https://www.youtube.com/watch?v=bC7NYmojsd4&t ...
openaire   +3 more sources

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

open access: yesGlia, EarlyView.
Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj   +5 more
wiley   +1 more source

Oculodentodigital Dysplasia Presenting as Spastic Ataxic Syndrome in an Indian Patient

open access: yesAnnals of Indian Academy of Neurology
Spastic ataxic syndrome is a combination of cerebellar ataxia with spasticity and other pyramidal features. Common causes of spastic ataxic syndrome include spinocerebellar ataxia (SCA) 1, SCA2, autosomal recessive ataxia of Charlevoix–Saguenay ...
Gosala RK Sarma   +3 more
doaj   +1 more source

A COMPARATIVE STUDY ON EFFECTIVENESS OF OPEN VERSUS CLOSED KINETIC CHAIN EXERCISES TO IMPROVE GAIT IN SPASTIC DIPLEGIC CEREBRAL PALSY

open access: yesInternational Journal of Physiotherapy, 2016
Background: Cerebral Palsy (CP) describes a non- progressive but not unchanging disorder of movement and posture due to an insult to or anomaly of the developing brain.
Dr. Trishna Saikia Baruah   +3 more
doaj   +1 more source

Evaluating the Intensity of Muscle Contraction by Near‐Infrared Spectroscopy, a Potential Application for Scaling Muscle Spasm

open access: yesJournal of Biophotonics, EarlyView.
Near‐infrared spectroscopy (NIRS) offers a novel, non‐invasive method to assess muscle spasticity. By measuring the Tissue Oxygenation Index (TOI) during different levels of muscle contraction, this study explores the feasibility of NIRS as an objective tool for spasticity evaluation.
Mehdi Nourizadeh   +8 more
wiley   +1 more source

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