Results 11 to 20 of about 121,621 (353)

A Novel SACS Variant Identified in a Chinese Patient: Case Report and Review of the Literature

open access: yesFrontiers in Neurology, 2022
Mutations in the SACS gene have been linked to autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS). It is a clinically and genetically heterogeneous disease characterized by slow progressive ataxia, spasticity, sensorimotor neuropathy, and
Yuchao Chen   +10 more
doaj   +1 more source

Hereditary Spastic Paraplegia Mimicking Cerebral Palsy-Heterozygous Mutation in ALDH18A1 [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Spastic paraplegias are characterised by progressive rigidity and weakness of the lower limbs. Spastic paraplegia is a standard differential diagnosis for spastic diplegic cerebral palsy.
Amit S Vatkar   +4 more
doaj   +1 more source

Is the Outcome of Diagnostic Nerve Block Related to Spastic Muscle Echo Intensity? A Retrospective Observational Study on Patients with Spastic Equinovarus Foot

open access: yesJournal of Rehabilitation Medicine, 2022
Objective: To investigate the relationship between spastic calf muscles echo intensity and the outcome of tibial nerve motor branches selective block in patients with spastic equinovarus foot. Design: Retrospective observational study.
Mirko Filippetti   +6 more
doaj   +1 more source

Correlation of Prechtl Qualitative Assessment of General Movement Analysis with Neurological Evaluation: The Importance of Inspection in Infants

open access: yesTürk Nöroloji Dergisi, 2019
Objective: Motor development is at the forefront of evaluation of neurodevelopmental functions in the first 6 months of life. Significant spontaneous movement patterns of infants are called general movements.
Nihan Hande Akcakaya   +4 more
doaj   +1 more source

The Effects of Botulinum Toxin Injections on Spasticity and Motor Performance in Chronic Stroke with Spastic Hemiplegia

open access: yesToxins, 2020
Spastic muscles are weak muscles. It is known that muscle weakness is linked to poor motor performance. Botulinum neurotoxin (BoNT) injections are considered as the first-line treatment for focal spasticity.
Yen-Ting Chen   +8 more
semanticscholar   +1 more source

Anxiety and Startle Phenotypes in Glrb Spastic and Glra1 Spasmodic Mouse Mutants

open access: yesFrontiers in Molecular Neuroscience, 2020
A GWAS study recently demonstrated single nucleotide polymorphisms (SNPs) in the human GLRB gene of individuals with a prevalence for agoraphobia. GLRB encodes the glycine receptor (GlyRs) β subunit.
Natascha Schaefer   +8 more
doaj   +1 more source

Spasticity-spastic movement disorder [PDF]

open access: yesSpinal Cord, 2008
Antispastic medications that are directed to reduce clinical signs of spasticity, such as exaggerated reflexes and muscle tone, do not improve the movement disorder. Medication can even increase weakness which might interfere with functional movements, such as walking.
openaire   +2 more sources

Intracortical Circuits in the Contralesional Primary Motor Cortex in Patients With Chronic Stroke After Botulinum Toxin Type A Injection: Case Studies

open access: yesFrontiers in Human Neuroscience, 2020
Spasticity and motor recovery are both related to neural plasticity after stroke. A balance of activity in the primary motor cortex (M1) in both hemispheres is essential for functional recovery. In this study, we assessed the intracortical inhibitory and
Maryam Zoghi   +7 more
doaj   +1 more source

Flaccid paraplegia of organophosphate-induced delayed polyneuropathy leading to early spastic paraplegia. Case report

open access: yesAktualności Neurologiczne, 2015
Organophosphate insecticides have been widely used for pest control. They have been readily used as a suicidal agent in developing countries. This paper reports the case of a middle aged male patient with acute organophosphate compound poisoning who in
Rohan Mahale   +4 more
doaj   +1 more source

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