Results 21 to 30 of about 71,305 (285)

Not all Forms of Muscle Hypertonia Worsen With Fatigue: A Pilot Study in Para Swimmers

Frontiers in Physiology, 2022
In hypertonic muscles of patients with upper motor neuron syndrome (UMNS), investigation with surface electromyography (EMG) with the muscle in a shortened position and during passive muscle stretch allows to identify two patterns underlying hypertonia ...
Luca Puce, Nicola Luigi Bragazzi, Antonio Currà, Lucio Marinelli, Lucio Marinelli, Laura Mori, Laura Mori, Filippo Cotellessa, Filippo Cotellessa, Karim Chamari, Karim Chamari, Marta Ponzano, Mohammad Hossein Samanipour, Pantelis T. Nikolaidis, Carlo Biz, Pietro Ruggieri, Carlo Trompetto, Carlo Trompetto   +17 more
doaj   +1 more source

Speech signal analysis and pattern recognition in diagnosis of dysarthria

Annals of Indian Academy of Neurology, 2017
Background: Dysarthria refers to a group of disorders resulting from disturbances in muscular control over the speech mechanism due to damage of central or peripheral nervous system.
Minu George Thoppil, C Santhosh Kumar, Anand Kumar, John Amose   +3 more
doaj   +1 more source

Demographic and Clinical Characteristics of Patients with Cerebral Palsy

İstanbul Medical Journal, 2018
Introduction: The purpose of this study was to identify the demographic and clinical characteristics of patients with cerebral palsy (SP) who applied to the Physical Therapy and Rehabilitation Center and to increase the awareness of physicians and ...
Hamza Sucuoğlu
doaj   +1 more source

Rescue axonal defects by targeting mitochondrial dynamics in hereditary spastic paraplegias

Neural Regeneration Research, 2019
Impaired axonal development and degeneration underlie debilitating neurodegenerative diseases including hereditary spastic paraplegia, a large group of inherited diseases.
Yongchao Mou, Xue-Jun Li
doaj   +1 more source

Research progress on limb spasmolysis, orthopedics and functional reconstruction of brain-derived paralysis

Journal of Neurorestoratology, 2021
Brain-derived paralysis is a disease dominated by limb paralysis caused by various brain diseases. The damage of upper motor neurons can lead to spastic paralysis of the limbs in different parts.
HaiLong Zhang, JianWen Zhi, Bo Ning, ShaoCheng Zhang   +3 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source

Differences of respiratory function in children with spastic diplegic and hemiplegic cerebral palsy, compared with normally developed children

Journal of Pediatric Rehabilitation Medicine, 2013
PURPOSE: The purpose of this study was to investigate differences between respiratory function in children with spastic cerebral palsy (CP) and children with normal development, and to compare respiratory function between children with spastic diplegic ...
Yong Hyun Kwon, Hye Young Lee
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source