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Parkinsonism and spastic paraplegia type 7: Expanding the spectrum of mitochondrial Parkinsonism

Movement Disorders, 2019
Pathogenic variants in the spastic paraplegia type 7 gene cause a complicated hereditary spastic paraplegia phenotype associated with classical features of mitochondrial diseases, including ataxia, progressive external ophthalmoplegia, and deletions of ...
Montserrat Ruiz   +2 more
exaly   +2 more sources

Spasticity

Current Treatment Options in Neurology, 2009
Treatment of spasticity requires a team approach, including the patient and caregivers, therapists, physicians, and surgeons. The team needs to determine what component of the spasticity interferes with function. Traditional therapy continues to dominate the therapy provided to patients who are living with spasticity.
Allison, Brashear, Kelly, Lambeth
openaire   +4 more sources

Spasticity

2012
Antispastic medications that are directed to reduce clinical signs of spasticity, such as exaggerated reflexes and muscle tone, do not improve the movement disorder. Medication can even increase weakness which might interfere with functional movements, such as walking.
Dietz, Volker, Sinkjaer, Thomas
openaire   +5 more sources

Spasticity

Clinical Orthopaedics and Related Research, 1987
Spasticity has been defined as velocity-dependent hyperactivity of stretch reflexes; it is therefore only one aspect of the complex syndrome produced by a lesion of the upper motoneuron. Although spasticity may be partially responsible for joint contractures, it does not produce most of the functional disability experienced by patients with upper ...
R R, Young, A W, Wiegner
openaire   +2 more sources

Measurement of Spasticity

Physical & Occupational Therapy In Pediatrics, 1988
Spasticity is generally defined as velocity-dependent increased resistance during passive movement of peripheral joints owing to increased involuntary muscle activity. However, the word spasticity is clinically used to describe a constellation of symptoms that arise secondary to the upper motor neuron (UMN) syndrome associated with a wide variety of ...
Mary Law, David Cadman
openaire   +2 more sources

Spasticity management in the child with spastic quadriplegia

European Journal of Neurology, 2001
In children with spastic quadriplegia, also described as ‘whole body involvement’, spasticity can interfere with motor function, contributes to the development of deformities and adversely impacts on care, positioning, and comfort. In this population, spasticity interventions address goals such as improving comfort, reducing pain, easing the burden of ...
L. Piccini   +2 more
openaire   +3 more sources

A comprehensive person-centered approach to adult spastic paresis: a consensus-based framework.

European Journal of Physical and Rehabilitation Medicine, 2018
Spastic paresis is a common feature of an upper motor neuron impairment caused by stroke, brain injury, multiple sclerosis and other central nervous system (CNS) disorders. Existing national and international guidelines for the treatment of adult spastic
L. Turner-Stokes   +11 more
semanticscholar   +1 more source

Neurosurgery for Spasticity

Stereotactic and Functional Neurosurgery, 2000
Spasticity is usually a useful substitute for deficiency of motor strength. However not infrequently, it may become harmful leading to an aggravation of motor disability. When excessive spasticity is not sufficiently controlled by physical therapy and pharmacological treatment, patients can have recourse to neurosurgery: neurostimulation, intrathecal ...
Marc Sindou, Patrick Mertens
openaire   +3 more sources

Spasticity and contractures

2019
This chapter discusses spasticity, a positive feature of disruption of the upper motor neuron pathways following acquired brain injury. After defining spasticity, it covers the prevalence and impact on limb function, methods of measurement (to monitor the outcomes of rehabilitation), goal setting, and management.
Sivan, Manoj   +3 more
openaire   +2 more sources

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