Results 51 to 60 of about 121,621 (353)

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Modeling and Identification of Mechanical and Reflex Properties related to Spasticity in Stroke Patients using Multiple Pendulum Tests

Journal of Biomechanical Science and Engineering, 2011
We propose a method for the comprehensive identification of spastic and intrinsic properties of spastic knee joints using multiple pendulum tests. The stretch reflex system was modeled as a velocity feedback loop where the key component was the muscle ...
Chul-Seung KIM, Gwang-Moon EOM, Kazunori HASE   +2 more
doaj   +1 more source

Relief of post-stroke spasticity with acute vibrotactile stimulation: controlled crossover study of muscle and skin stimulus methods

Frontiers in Human Neuroscience, 2023
BackgroundPrior work suggests that vibratory stimulation can reduce spasticity and hypertonia. It is unknown which of three predominant approaches (stimulation of the spastic muscle, antagonist muscle, or cutaneous regions) most reduces these symptoms ...
Caitlyn Seim, Bingxian Chen, Chuzhang Han, David Vacek, Laura Song Wu, Maarten Lansberg, Allison Okamura   +6 more
doaj   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Unilateral Ankle‐Foot Exoneuromusculoskeleton with Balance‐Sensing Feedback for Self‐Help Telerehabilitation after Stroke

Advanced Robotics Research, EarlyView.
This study introduces a hybrid robot that integrates mechanical assistance by musculoskeletons (i.e., soft pneumatic muscle with rigid exoskeletal extensions), neuromuscular electrical stimulation, and vibrotactile feedback in a lightweight wearable mechatronic complex applicable to the paretic ankle–foot poststroke for gait restoration. The system can
Fuqiang Ye, Wei Rong, Waiming Li, Kwok‐Ting Wong, Man‐Kit Pang, Hon‐Wah Wai, Lilly Li, Zicong Hong, Song Guo, Zong‐Hao Ma, Yongping Zheng, Ming Zhang, Nicholas Chow, Jianing Zhang, Xiaoling Hu, Fei Chen, Waisang Poon   +16 more
wiley   +1 more source

INTERDISCIPLINARY TREATMENT FROM CHILDREN WITH SPASTIC TETRAPARESIS

Sport şi Societate, 2017
Purpose: In paralysis spastic cerebral treatment outcome will be mostly below normal. It is difficult to assess to what extent the functional capacity contributed treatment or development of the nervous system itself.
Ștefan TOMA, Geanina TOMA
doaj  

Influence of Botulinum Toxin Therapy on Postural Control and Lower Limb Intersegmental Coordination in Children with Spastic Cerebral Palsy

Toxins, 2013
Botulinum toxin injections may significantly improve lower limb kinematics in gait of children with spastic forms of cerebral palsy. Here we aimed to analyze the effect of lower limb botulinum toxin injections on trunk postural control and lower limb ...
Bernard Dan, Guy Cheron, Ronald Buyl, Linda de Meirleir, Eric Kerckhofs, Marc Degelaen, Ludo de Borre   +6 more
doaj   +1 more source

Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.

Journal of Clinical Investigation, 2014
Autophagy allows cells to adapt to changes in their environment by coordinating the degradation and recycling of cellular components and organelles to maintain homeostasis. Lysosomes are organelles critical for terminating autophagy via their fusion with
Jaerak Chang, Seongju Lee, C. Blackstone
semanticscholar   +1 more source

Spasticity Mechanisms – for the Clinician [PDF]

Frontiers in Neurology, 2010
Spasticity, a classical clinical manifestation of an upper motor neuron lesion, has been traditionally and physiologically defined as a velocity dependent increase in muscle tone caused by the increased excitability of the muscle stretch reflex.
A Mukherjee, Ambar Chakravarty
openaire   +4 more sources

Enhancing Grasping Function with a Thermoresponsive Ionogel Adhesive Glove for Patients with Rheumatic Diseases

Advanced Science, EarlyView.
This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang, Shiqing Liu, Jingfeng Zhang, Zhouyang Yu, Yifan Shao, Cong Zhao, Jiahong Ma, Xin Fu, Mengqi Yang, Lie Chen, Mingjie Liu, Li Wen   +11 more
wiley   +1 more source