Results 91 to 100 of about 3,145,207 (318)
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
One of the goals of learning geography is to give students the ability to think spatially. But based on observations in the field, it shows that students' spatial thinking skills have not shown maximum results.
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Spatial clustering method for geographic data
In the process of visualizing quantitative spatial data, it is necessary to classify attribute values into some class divisions. In a previous paper, the author proposed a classification method for minimizing the loss of information contained in ...
Osaragi, Toshihiro
core
Exposure to significant levels of stress and trauma throughout life is a leading risk factor for the development of major psychiatric disorders. Despite this, we do not have a comprehensive understanding of the mechanisms that explain how stress raises ...
Amber R. Curry +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The accompanying paper provided evidence to suggest that spatial variability of groundwater recharge is ‘true’ variability. This paper attempts to determine the major causes of such variability even at small distances, if there appear to be a frequency ...
De Silva, RP
core
Vertices 6—spatial@ucsb eNews [PDF]
This issue of Vertices highlights the transition in leadership of the Center for Spatial Studies from Michael Goodchild (geographer and founder of the Center) to Mary Hegarty (psychologist and scholar of spatial cognition.Special attention is given to ...
Center for Spatial Studies, UCSB
core
Introduction: Bunaken Island still lacks proper waste management infrastructure, resulting in the accumulation of garbage around residences and along the coastline.
Agus Bintara Birawida +5 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

