Results 81 to 90 of about 3,900,726 (310)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Workbook for Quantitative Methods and Socio-Economic Applications in GIS
This webinar will introduce the project on "the Workbook for Quantitative Methods and Socioconomic Application in GIS", and how to join the spatial data lab on those ongoing spacial social science research and development ...
Spatial, Data Lab
core +1 more source
QUT Spatial Science Students Celebrate Awards [PDF]
, 2008 Article contains details about students from Spatial Science at QUT celebrating academic and industry sponsored awards from BEE faculty student prizes ...
Webb, Robert M.
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Spatial Search, Position Papers [PDF]
, 2014 The Spatial Search specialist meeting in Santa Barbara (December 2014) brought together 35 academic and industry representatives from computational, geospatial, and cognitive sciences with interest in focused discussions on the development of an ...
Center for Spatial Studies, UCSB
core +1 more source
Queensland Spatial Excellence Awards 2009 : individual citations [PDF]
, 2009 Profesional Citation with address to Spatial Sciences Institution (Queensland) - Education and Professional Development Criteria; including Executive Summary, Teaching, Research, Publications Summary, Professional Service and ...
Webb, Robert M.
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Spatial Science News from QUT April 2011 [PDF]
, 2011 Multiple awards for Spatial/Surveying lecturer, raising entry quality and commencing numbers at QUT, Gardens Point rapt in promise of things to come, STEM building ...
Webb, Robert M.
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source