Results 181 to 190 of about 1,688,232 (308)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Genomic and spatial analysis of local recurrences following risk-adapted breast radiotherapy in the IMPORT trials. [PDF]

Breast Cancer Res
Lightowlers SV, Roman-Escorza M, Welsh C, Bliss JM, Carroll JS, Chan HYC, Harrison K, Haviland JS, Healy N, Jefford ML, Jena R, Kirby AM, Kirwan CC, Provenzano E, Sydenham MA, Syndikus I, Tanner J, Woitek R, Coles CE, Sawyer EJ.   +19 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Adaptive ensemble spatial analysis. [PDF]

Sci Rep
Egaña AF, Valenzuela MJ, Maleki M, Sánchez-Pérez JF, Díaz G.   +4 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Landscape determinants of human-elephant conflict in Assam, India: insights from two decades of spatial analysis. [PDF]

PeerJ
G AN, Pandey RK, Roy K, Dutta A, Mittal D, Nigam P, Nath A, Habib B.   +7 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Histolytics: A panoptic spatial analysis framework for interpretable histopathology. [PDF]

Comput Struct Biotechnol J
Lehtonen O, Nordlund N, Salloum S, Kalliala I, Virtanen A, Hautaniemi S.   +5 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Spatial analysis of physical activity and ambient air pollution in Kuwait: a cross-sectional study. [PDF]

Sci Rep
Feyissa TR, Oguoma VM, Alsharrah S, Schroers RD, Al-Mulla F, Daniel M.   +5 more
europepmc   +1 more source