Results 51 to 60 of about 4,294,785 (258)

The Application of WebGIS Tools for Visualizing Coastal Flooding Vulnerability and Planning for Resiliency: The New Jersey Experience

open access: yesISPRS International Journal of Geo-Information, 2014
While sea level rise is a world-wide phenomenon, mitigating its impacts is a local decision-making challenge that is going to require site-specific remedies.
Richard Lathrop   +3 more
doaj   +1 more source

Understanding the Role of Optimized Land Use/Land Cover Components in Mitigating Summertime Intra-Surface Urban Heat Island Effect: A Study on Downtown Shanghai, China

open access: yesEnergies, 2020
In this study, 167 land parcels of downtown Shanghai, China, were used to investigate the relationship between parcel-level land use/land cover (LULC) components and associated summertime intra-surface urban heat island (SUHI) effect, and further analyze
Yan-jun Guo   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A spatial analysis of multivariate output from regional climate models [PDF]

open access: yes, 2011
Climate models have become an important tool in the study of climate and climate change, and ensemble experiments consisting of multiple climate-model runs are used in studying and quantifying the uncertainty in climate-model output.
Cressie, Noel   +2 more
core   +3 more sources

Modelling Global Deforestation Using Spherical Geographic Automata Approach

open access: yesISPRS International Journal of Geo-Information, 2023
Deforestation as a land-cover change process is linked to several environmental problems including desertification, biodiversity loss, and ultimately climate change.
Bright Addae, Suzana Dragićević
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Determinants of Spatial Distribution of Organic Farming in Germany [PDF]

open access: yes, 2005
The share of organically managed land is spread unevenly throughout Germany and shows pronounced regional concentrations. The spatial distribution of organic farming is assumed to be influenced by several factors. Location factors of farms are regionally
Bichler, Barbara   +3 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Quantifying Retail Agglomeration using Diverse Spatial Data

open access: yesScientific Reports, 2017
Newly available data on the spatial distribution of retail activities in cities makes it possible to build models formalized at the level of the single retailer.
Duccio Piovani   +2 more
doaj   +1 more source

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