Results 51 to 60 of about 4,294,785 (258)
While sea level rise is a world-wide phenomenon, mitigating its impacts is a local decision-making challenge that is going to require site-specific remedies.
Richard Lathrop +3 more
doaj +1 more source
In this study, 167 land parcels of downtown Shanghai, China, were used to investigate the relationship between parcel-level land use/land cover (LULC) components and associated summertime intra-surface urban heat island (SUHI) effect, and further analyze
Yan-jun Guo +4 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A spatial analysis of multivariate output from regional climate models [PDF]
Climate models have become an important tool in the study of climate and climate change, and ensemble experiments consisting of multiple climate-model runs are used in studying and quantifying the uncertainty in climate-model output.
Cressie, Noel +2 more
core +3 more sources
Modelling Global Deforestation Using Spherical Geographic Automata Approach
Deforestation as a land-cover change process is linked to several environmental problems including desertification, biodiversity loss, and ultimately climate change.
Bright Addae, Suzana Dragićević
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Determinants of Spatial Distribution of Organic Farming in Germany [PDF]
The share of organically managed land is spread unevenly throughout Germany and shows pronounced regional concentrations. The spatial distribution of organic farming is assumed to be influenced by several factors. Location factors of farms are regionally
Bichler, Barbara +3 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Quantifying Retail Agglomeration using Diverse Spatial Data
Newly available data on the spatial distribution of retail activities in cities makes it possible to build models formalized at the level of the single retailer.
Duccio Piovani +2 more
doaj +1 more source

