Results 51 to 60 of about 1,677,553 (308)

Predicting future landslides for risk analysis - spatial models and cross-validation of their results

, 2008
A landslide-hazard map is intended to show the location of future slope instability. Most spatial models of the hazard lack reliability tests of the procedures and predictions for estimating the probabilities of future landslides, thus precluding use of ...
Chung, C.F., Fabbri, A.G.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Scaling Beyond Cities

Frontiers in Physics, 2022
City population size is a crucial measure when trying to understand urban life. Many socio-economic indicators scale superlinearly with city size, whilst some infrastructure indicators scale sublinearly with city size.
Rafael Prieto Curiel, Rafael Prieto Curiel, Carmen Cabrera-Arnau, Steven Richard Bishop   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Is transport modelling ‘a bit of a racket’? On the role of transport planning support systems in England

Transportation Research Interdisciplinary Perspectives
As transport planning support systems (TPSS) such as models, frameworks and dashboards grow in prevalence among devolved, combined and regional authorities, it is essential to understand how these systems are being applied, and the institutional ...
Claude E.H. Lynch, Gerard Casey, Esra Suel, Adam Dennett   +3 more
doaj   +1 more source

The yield gap of global grain production: A spatial analysis

, 2010
Global grain production has increased dramatically during the past 50 years, mainly as a consequence of intensified land management and introduction of new technologies.
Stehfest, E., Müller, C., Verburg, P.H., Verburg, P.H.; id_orcid, Neumann, K.   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Land use–transport interaction modeling: A review of the literature and future research directions

Journal of Transport and Land Use, 2015
The aim of this review paper is to provide comprehensive and up-to-date material for both researchers and practitioners interested in land-use-transport interaction (LUTI) modeling.
Ransford Antwi Acheampong, Elisabete Silva   +1 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source