Results 51 to 60 of about 4,349,499 (279)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Application of WebGIS Tools for Visualizing Coastal Flooding Vulnerability and Planning for Resiliency: The New Jersey Experience

open access: yesISPRS International Journal of Geo-Information, 2014
While sea level rise is a world-wide phenomenon, mitigating its impacts is a local decision-making challenge that is going to require site-specific remedies.
Richard Lathrop   +3 more
doaj   +1 more source

Understanding the Role of Optimized Land Use/Land Cover Components in Mitigating Summertime Intra-Surface Urban Heat Island Effect: A Study on Downtown Shanghai, China

open access: yesEnergies, 2020
In this study, 167 land parcels of downtown Shanghai, China, were used to investigate the relationship between parcel-level land use/land cover (LULC) components and associated summertime intra-surface urban heat island (SUHI) effect, and further analyze
Yan-jun Guo   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Modelling Global Deforestation Using Spherical Geographic Automata Approach

open access: yesISPRS International Journal of Geo-Information, 2023
Deforestation as a land-cover change process is linked to several environmental problems including desertification, biodiversity loss, and ultimately climate change.
Bright Addae, Suzana Dragićević
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An Overview of Spatial Econometrics

open access: yes, 2016
This paper offers an expository overview of the field of spatial econometrics. It first justifies the necessity of special statistical procedures for the analysis of spatial data and then proceeds to describe the fundamentals of these procedures.
Tybl, Alexander J.
core   +1 more source

Spatial pattern formation induced by Gaussian white noise [PDF]

open access: yes, 2011
The ability of Gaussian noise to induce ordered states in dynamical systems is here presented in an overview of the main stochastic mechanisms able to generate spatial patterns.
D'Odorico, Paolo   +3 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

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