Results 61 to 70 of about 5,920,185 (311)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Readout from iconic memory involves similar neural processes as selective spatial attention [PDF]
, 2007 Iconic memory and spatial attention are often considered as distinct topics, but may have functional similarities. Here we provide fMRI evidence for some common underlying neural effects.
Kristjansson, A, Ruff, CC, Driver, J
core
Changes in the spatial spread of attention with ageing [PDF]
, 2018 Spatial attention is a necessary cognitive process, allowing for the direction of limited capacity resources to varying locations in the visual field for improved visual processing. Thus, understanding how ageing influences these processes is vital.
Lawrence, Rebecca +4 more
core +1 more source
The Spatial Resolution of Visual Attention
Cognitive Psychology, 2001 Two tasks were used to evaluate the grain of visual attention, the minimum spacing at which attention can select individual items. First, observers performed a tracking task at many viewing distances. When the display subtended less than 1 degrees in size, tracking was no longer possible even though observers could resolve the items and their motions ...
J, Intriligator, P, Cavanagh
openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The control of attention to faces [PDF]
, 2007 Humans attend to faces. This study examines the extent to which attention biases to faces are under top-down control. In a visual cueing paradigm, observers responded faster to a target probe appearing in the location of a face cue than of a competing ...
Burton, A. Mike +8 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Tactile spatial attention enhances gamma-band activity in somatosensory cortex and reduces low-frequency activity in parieto-occipital areas. [PDF]
, 2006 We investigated the effects of spatial-selective attention on oscillatory neuronal dynamics in a tactile delayed-match-to-sample task. Whole-head magnetoencephalography was recorded in healthy subjects while dot patterns were presented to their index ...
Bauer, M +3 more
core
Finding the Answer in Space: The Mental Whiteboard Hypothesis on Serial Order in Working Memory
Frontiers in Human Neuroscience, 2014 Various prominent models on serial order coding in working memory build on the notion that serial order is achieved by binding the various items to-be-maintained to fixed position markers.
Elger eAbrahamse +3 more
doaj +1 more source
Ship Object Detection of Remote Sensing Image Based on Visual Attention
Remote Sensing, 2021 At present, reliable and precise ship detection in high-resolution optical remote sensing images affected by wave clutter, thin clouds, and islands under complex sea conditions is still challenging.
Yuxin Dong +3 more
doaj +1 more source