Results 151 to 160 of about 1,951,035 (294)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Incorporating virtual fencing to manage yearling steers on extensive rangelands: spatial behavior, growth performance, and enteric methane emissions. [PDF]

Front Vet Sci
Raynor EJ, Shadbolt AM, Johnston MK, Augustine DJ, Derner JD, Kearney SP, Ritten JP, Delay ND, Carvalho PHV, Vargas JJ, Place SE, Stackhouse-Lawson KR.   +11 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

The Projection-Specific Noradrenergic Modulation of Perseverative Spatial Behavior in Adult Male Rats. [PDF]

eNeuro
Kabanova A, Fedorov L, Eschenko O.
europepmc   +1 more source

Spatial behavior and habitat use in widely separated breeding and wintering distributions across three species of long-distance migrant Phylloscopus warblers. [PDF]

Ecol Evol, 2019
Lerche-Jørgensen M, Mallord JW, Willemoes M, Orsman CJ, Roberts JT, Skeen RQ, Eskildsen DP, Salewski V, Tøttrup AP, Thorup K.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Development of a multisensor biologging collar and analytical techniques to describe high-resolution spatial behavior in free-ranging terrestrial mammals. [PDF]

Ecol Evol
Painter MS, Silovský V, Blanco J, Holton M, Faltusová M, Wilson R, Börger L, Psotta L, Ramos-Almodovar F, Estrada L, Landler L, Malkemper P, Hart V, Ježek M.   +13 more
europepmc   +1 more source

Extinction and spontaneous recovery of spatial behavior in pigeons. [PDF]

J Exp Psychol Anim Learn Cogn, 2015
Leising KJ, Wong J, Blaisdell AP.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source