Results 41 to 50 of about 617,742 (295)
Spatial-temporal clustering of an outbreak of SARS-CoV-2 Delta VOC in Guangzhou, China in 2021
Frontiers in Public Health, 2022 BackgroundIn May 2021, the SARS-CoV-2 Delta variant led to the first local outbreak in China in Guangzhou City. We explored the epidemiological characteristics and spatial-temporal clustering of this outbreak.MethodsBased on the 153 cases in the SARS-CoV-
Qian Zhang +31 more
doaj +1 more source
Finding spatial clusters [PDF]
, 1997 The special challenge in analysing geographical data comes from the spatial distribution of the objects. We are interested here in finding out whether a given property is randomly distributed or concentrated somewhere. More exactly: consider a two-dimensional region subdivided into non-overlapping fields, e. g. a state divided into counties, and assume
openaire +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A novel variable neighborhood search approach for cell clustering for spatial transcriptomics
GigaByteThis paper introduces a new approach to cell clustering using the Variable Neighborhood Search (VNS) metaheuristic. The purpose of this method is to cluster cells based on both gene expression and spatial coordinates.
Aleksandra Djordjevic +4 more
doaj +1 more source
New Journal of Physics, 2020 We analyse the spatial inhomogeneities (‘spatial clustering’) in the distribution of particles accelerated by a force that changes randomly in space and time.
J Meibohm, K Gustavsson, J Bec, B Mehlig
doaj +1 more source
Frontiers in Public Health, 2023 ObjectiveThis study attempts to analyze the spatial clustering and spatial-temporal distribution characteristics of hepatitis E (HE) at the county (city and district) level in Jiangsu province to provide a scientific basis for the prevention and control ...
Yao Shi +7 more
doaj +1 more source
The Impact of Global Clustering on Spatial Database Systems [PDF]
, 1994 Global clustering has rarely been investigated in the area of spatial database systems although dramatic performance improvements can be achieved by using suitable techniques.
Brinkhoff, Thomas, Kriegel, Hans-Peter
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Spatial clustering of array CGH features in combination with hierarchical multiple testing [PDF]
, 2010 We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering: joining contiguous,
Kim, Kyung In +2 more
core +6 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source