Results 101 to 110 of about 509,427 (264)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Spatial context and visual perception for action
Psicológica, 2005 In this paper, evidences that visuo-spatial perception in the peri-personal space is not an abstract, disembodied phenomenon but is rather shaped by action constraints are reviewed.
Yann Coello
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Spatial Effects in the Context of Kazakhstan’s Regions
Экономика: стратегия и практикаThe problem of spatial inequality in the regions of Kazakhstan has been relevant for many years and in recent years this problem has worsened due to socio-economic changes in the areas, the consequences of the COVID-19 pandemic, the negative impact of ...
A. R. Kerimbayev +3 more
doaj +1 more source
Background check: cross-cultural differences in the spatial context of comic scenes. [PDF]
Multimodal Commun, 2023 Atilla F, Klomberg B, Cardoso B, Cohn N.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Diversified Retrieval of Spatial Data with Context.
, 2022 The abundance and ubiquity of spatial datasets necessitates their effective and efficient retrieval. For instance, on the web, there are datasets with GIS objects or POIs (e.g. Spatialhadoop datasets), datasets with geo-tagged photographs (e.g. Flickr), online social networks (e.g. Facebook), and semantic knowledge graphs (e.g. Yago, DBpedia).
openaire +2 more sources
Protocol for multispectral imaging on cryosections to map myeloid cell heterogeneity in its spatial context. [PDF]
STAR Protoc, 2023 Wieland EB +5 more
europepmc +1 more source