Results 131 to 140 of about 2,181,625 (282)

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

The Role of Cultural Landscape in Shaping the Urban Spatial Context of Changzhou (1843–2021) from a Spatial Syntax Perspective

open access: yesLand
Changzhou is a city situated in the eastern region of China and serves as a pivotal juncture of the UNESCO World Cultural Heritage site, the Grand Canal of China. The study employed spatial syntax foreground and background network analysis to examine the
Jie Bai   +5 more
doaj   +1 more source

Voronoi-Based Region Approximation for Geographical Information Retrieval with Gazetteers

open access: yes, 2001
Gazetteers and geographical thesauri can be regarded as parsimonious spatial models that associate geographical location with place names and encode some semantic relations between the names.
Alani, Harith   +2 more
core  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

A spatial model based on the endogenous growth theory for Portugal. Another approach [PDF]

open access: yes
We built a model analyzing, through cross-section estimation methods, the influence of spatial effects in the conditional product convergence in the parishes’ economies of mainland Portugal between 1991 and 2001 (the last year with data available for ...
Martinho, Vítor João Pereira Domingues
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Unsupervised feature correlation-based spatial stratification for local context-aware modelling

open access: yesGIScience & Remote Sensing
Context-aware modelling improves the accuracy of spatial inferences through using local environmental conditions, spatial dependency, and heterogeneity. However, traditional context-aware approaches generally require constructing separate models for each
Jinyu Meng, Zengchuan Dong, Yongze Song
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Protocol for multispectral imaging on cryosections to map myeloid cell heterogeneity in its spatial context. [PDF]

open access: yesSTAR Protoc, 2023
Wieland EB   +5 more
europepmc   +1 more source

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