Results 91 to 100 of about 5,373,647 (264)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

3D MIMO channel modeling and simulations

open access: yesDianxin kexue, 2016
The existing MIMO channel simulation models are based on two-dimensional(2D)plane and can’t match with a three-dimensional(3D)radio propagation environment.A 3D MIMO channel simulation platform based on WINNER channel model was set up.After adding the ...
Xiongwen ZHAO   +4 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A spatial model of the Keynesian theory for Portugal [PDF]

open access: yes
With this work we try to present a spatial model for Portugal based on the Keynesian theory. We built the model analysing, through cross-section estimation methods, the influence of spatial effects in productivity in the NUTs III economic sectors of ...
Martinho, Vítor João Pereira Domingues
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Improved tests for spatial correlation [PDF]

open access: yes, 2012
We consider testing the null hypothesis of no spatial autocorrelation against the alternative of first order spatial autoregression. A Wald test statistic has good first order asymptotic properties, but these may not be relevant in small or moderate ...
Robinson, Peter M.   +3 more
core   +1 more source

Improved coverage in WSNs by exploiting spatial correlation: the two sensor case

open access: yesEURASIP Journal on Advances in Signal Processing, 2011
One of the main applications of Wireless Sensor Networks (WSNs) is area monitoring. In such problems, it is desirable to maximize the area coverage. The main objective of this work is to investigate collaborative detection schemes at the local sensor ...
Michaelides Michalis   +1 more
doaj  

Structural Interactions in Spatial Panels [PDF]

open access: yes, 2009
Cross-sectional and spatial dependence, Spatial weights matrix, Spatial interactions, Monetary policy committee, Generalised method of moments, E42, E43, E50, E58,
Bhattacharjee, Arnab   +4 more
core   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Indirect inference in spatial autoregression

open access: yes, 2014
Ordinary least squares (OLS) is well-known to produce an inconsistent estimator of the spatial parameter in pure spatial autoregression (SAR). This paper explores the potential of indirect inference to correct the inconsistency of OLS.
Rossi, Francesca   +2 more
core   +1 more source

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