Results 101 to 110 of about 665,694 (315)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Improved coverage in WSNs by exploiting spatial correlation: the two sensor case

open access: yesEURASIP Journal on Advances in Signal Processing, 2011
One of the main applications of Wireless Sensor Networks (WSNs) is area monitoring. In such problems, it is desirable to maximize the area coverage. The main objective of this work is to investigate collaborative detection schemes at the local sensor ...
Michaelides Michalis   +1 more
doaj  

Spatial Autoregressive Models for House Price Dynamics in Italy [PDF]

open access: yes
This paper elaborates a Spatial Autoregressive and Spatial Error Model (SAR-SE Model) to investigate the Italian house price dynamics. House prices in real terms have been modelled for the period 1995-2008 in all the 103 Italian provinces along with ...
Tiziana Caliman, Enrico di Bella
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Indirect inference in spatial autoregression

open access: yes, 2014
Ordinary least squares (OLS) is well-known to produce an inconsistent estimator of the spatial parameter in pure spatial autoregression (SAR). This paper explores the potential of indirect inference to correct the inconsistency of OLS.
Rossi, Francesca   +2 more
core  

Structural Interactions in Spatial Panels

open access: yes, 2009
Cross-sectional and spatial dependence, Spatial weights matrix, Spatial interactions, Monetary policy committee, Generalised method of moments, E42, E43, E50, E58,
Bhattacharjee, Arnab   +4 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Impact of Capital Gains and Urban Pressure on Farmland Values: A Spatial Correlation Analysis

open access: yes
Farmland is a major component of wealth in the farm sector as well as wealth of farm households. This study contributes to our knowledge of variations in farmland prices by examining the extent to which farmland values are spatially correlated and to ...
Moss, Charles B.   +2 more
core  

Spatial circular matrices, with applications [PDF]

open access: yes
The cumulants of the quadratic forms associated to the so-called spatial design matrices are often needed for inference in the context of isotropic processes on uniform grids.
Federico Martellosio, Grant Hillier
core  

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