Results 91 to 100 of about 4,357,372 (295)

k-nearest neighbors prediction and classification for spatial data

, 2018
We propose a nonparametric predictor and a supervised classification based on the regression function estimate of a spatial real variable using k-nearest neighbors method (k-NN). Under some assumptions, we establish almost complete or sure convergence of
Ahmed, Mohamed-Salem, Attouch, Mohammed Kadi, Dabo-Niang, Sophie, N'diaye, Mamadou   +3 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Feasibility of a BIM-Driven Approach to Support Building Subdivision Workflows—Case Study of Victoria, Australia

ISPRS International Journal of Geo-Information, 2019
Cities are facing dramatic challenges due to population growth and the massive development of high-rises and complex structures, both above and below the ground surface. Decision-makers require access to an efficient land and property information system,
Hamed Olfat, Behnam Atazadeh, Davood Shojaei, Abbas Rajabifard   +3 more
doaj   +1 more source

Spatial Disaggregation of Agricultural Production Data [PDF]

In this paper we develop a dynamic data-consistent way for estimating agricultural land use choices at a disaggregate level (district-level), using more aggregate data (regional-level). The disaggregation procedure requires two steps.
Howitt, Richard E., Reynaud, Arnaud
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Image-to-Point Cloud Registration using Camera Motion Generation and Monocular Depth Estimation [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Image-to-point cloud (I2P) registration plays a vital role in applications requiring accurate spatial alignment between 2D images and their corresponding 3D point clouds.
M. Kamali, B. Atazadeh, A. Rajabifard, Y. Chen   +3 more
doaj   +1 more source

Modelling Spatial Autocorrelation in Spatial Interaction Data

SSRN Electronic Journal, 2007
Spatial interaction models of the gravity type are widely used to model origindestination flows. They draw attention to three types of variables to explain variation in spatial interactions across geographic space: variables that characterise an origin region of a flow, variables that characterise a destination region of a flow, and finally ...
Fischer, Manfred M., Griffith, Daniel A.
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of Political Economy on Land Administration Reform

Land
Population growth, urbanization and climate change are all factors that have made it increasingly difficult for governments to manage, allocate and permit the development and use of the finite land resource that is available in any society.
Anthony Francis Burns, Abbas Rajabifard, Davood Shojaei   +2 more
doaj   +1 more source