Results 71 to 80 of about 1,279,456 (262)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
International Journal of Health GeographicsBackground The COVID-19 pandemic caused substantial mortality in the United States with impacts unevenly distributed across the country. Official COVID-19-related death counts, however, almost certainly underrepresent the true impact of the pandemic due ...
Chen-Lun Kao, A. Stewart Fotheringham
doaj +1 more source
Impact of Political Economy on Land Administration Reform
LandPopulation growth, urbanization and climate change are all factors that have made it increasingly difficult for governments to manage, allocate and permit the development and use of the finite land resource that is available in any society.
Anthony Francis Burns +2 more
doaj +1 more source
ISPRS International Journal of Geo-Information, 2019 Cities are facing dramatic challenges due to population growth and the massive development of high-rises and complex structures, both above and below the ground surface. Decision-makers require access to an efficient land and property information system,
Hamed Olfat +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingWildfires cause substantial damage and present considerable risks to both natural ecosystem and human societies. A precise and prompt evaluation of wildfire-induced damage is crucial for effective postfire management and restoration.
Mingda Wu +4 more
doaj +1 more source
Image-to-Point Cloud Registration using Camera Motion Generation and Monocular Depth Estimation [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information SciencesImage-to-point cloud (I2P) registration plays a vital role in applications requiring accurate spatial alignment between 2D images and their corresponding 3D point clouds.
M. Kamali +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source