Results 131 to 140 of about 4,369,639 (344)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Assessing clustering methods for exploratory spatial data analysis [PDF]

open access: yes
Exploratory spatial data analysis continues to be an important area of research. The use and application of clustering methods for the analysis of spatially referenced data is beginning to show some promise.
Alan Murray
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

SI-Mamba: High-Resolution Sea Ice Recognition via RB-NDI Guided State-Space Model

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sea ice recognition is of great significance for reflecting climate change and ensuring ship navigation safety. In recent years, many deep learning-based methods have been proposed and applied to the segmentation and recognition of sea ice regions ...
Wenjun Hong   +7 more
doaj   +1 more source

Spatial Data Transfer Standard (SDTS) and Spatial Data Model

open access: yesTheory and Applications of GIS, 1994
The Spatial Data Transfer Standard (SDTS), also Federal Information Processing Standard 173, was designed to transfer the full range of spatial data (i.e. vector data, raster data of different models and structures). The SDTS approaches the difficult translation between different types of spatial data by defining a conceptual spatial data model, which ...
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Monitoring of Spatial Data Infraestructures

open access: yes, 2010
SDI monitoring and evaluation is increasingly attracting the attention of both public sector bureaucrats seeking justification for providing public sources to SDI and SDI practitioners requiring a measure of success of their SDI strategy.
Castelein, Watse   +1 more
core  

Home - About - Disclaimer - Privacy