Results 31 to 40 of about 613,971 (301)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

A Vision Language-Based Framework for Detecting Industrial Mechanical, Electrical, and Plumbing Assets Using Unlabelled Data

Sensors
There have been significant advancements in object detection using extensive labelled datasets. However, existing learning-based approaches remain constrained in industrial environments, primarily due to the limited diversity in training datasets; the ...
Masoud Kamali, Behnam Atazadeh, Abbas Rajabifard, Yiqun Chen, Ensiyeh Javaherian Pour   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A BIM-based Framework for Building Depreciation Estimation through Maintenance Management Integration [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This paper proposes a framework for dynamic depreciation estimation by integrating Building Information Modelling (BIM), cost estimation datasets and maintenance data from Computerized Maintenance Management Systems (CMMS) or Facility Management Systems (
P. Jafary, P. Jafary, D. Shojaei, A. Rajabifard, T. Ngo, T. Ngo   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

THE NEED FOR SPATIAL DATA INFRASTRUCTURE FOR SUSTAINABLE DEVELOPMENT IN TANZANIA

African Journal on Land Policy and Geospatial Sciences, 2021
This paper explores the use of spatial data in Tanzania, it underscores the reasons for lagging in the establishment of National Spatial Data Infrastructure.
Zakaria Robert Ngereja
doaj   +1 more source

Towards Scalable Visual Exploration of Very Large RDF Graphs

, 2015
In this paper, we outline our work on developing a disk-based infrastructure for efficient visualization and graph exploration operations over very large graphs.
A Dadzie, C Tominski, D Archambault, D Auber, J Abello, M Alonen, M Dudáš, M Zinsmaier, N Bikakis, P Heim, S Mazumdar, S Mazumdar   +11 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Structural Analysis Ready Building Information Modelling: A Requirement Analysis [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Structural analysis is utilised to evaluate the behaviour of structures under applied loads to ensure their safety and stability. It is crucial in designing, assessing, and retrofitting buildings and structures.
M. Akhoundi Khezrabad, D. Shojaei, M. Tomko   +2 more
doaj   +1 more source