Results 41 to 50 of about 115,628 (302)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A BIM-based Framework for Building Depreciation Estimation through Maintenance Management Integration [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This paper proposes a framework for dynamic depreciation estimation by integrating Building Information Modelling (BIM), cost estimation datasets and maintenance data from Computerized Maintenance Management Systems (CMMS) or Facility Management Systems (
P. Jafary, P. Jafary, D. Shojaei, A. Rajabifard, T. Ngo, T. Ngo   +5 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Zero-Shot 3D Asset Detection and Localisation Through Visual Grounding in Industrial Point Clouds

AI
3D scene understanding in industrial environments is crucial for effective operation and maintenance (O&M) and asset monitoring. However, accurate asset detection and localisation face significant challenges due to asset diversity and scene complexity in
Masoud Kamali, Behnam Atazadeh, Abbas Rajabifard, Yiqun Chen   +3 more
doaj   +1 more source

THE NEED FOR SPATIAL DATA INFRASTRUCTURE FOR SUSTAINABLE DEVELOPMENT IN TANZANIA

African Journal on Land Policy and Geospatial Sciences, 2021
This paper explores the use of spatial data in Tanzania, it underscores the reasons for lagging in the establishment of National Spatial Data Infrastructure.
Zakaria Robert Ngereja
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Relaunching the Kenya National Spatial Data Infrastructure

, 2017
Despite a history of more than 15 years, the Kenya National Spatial Data Infrastructure had largely stagnated in 2016. The national geoportal, often regarded as the face of a Spatial Data Infrastructure, was not even accessible.
Mwange, Collins, Siriba, David, Mulaku, Galcano C.   +2 more
core   +1 more source

Structural Analysis Ready Building Information Modelling: A Requirement Analysis [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Structural analysis is utilised to evaluate the behaviour of structures under applied loads to ensure their safety and stability. It is crucial in designing, assessing, and retrofitting buildings and structures.
M. Akhoundi Khezrabad, D. Shojaei, M. Tomko   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source