Results 41 to 50 of about 526,105 (299)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Three-Dimensional Rule-Based City Modelling to Support Urban Redevelopment Process

ISPRS International Journal of Geo-Information, 2018
Multi-dimensional representation of urban settings has received a great deal of attention among urban planners, policy makers, and urban scholars. This is due to the fact that cities grow vertically and new urbanism strategies encourage higher density ...
Tyler Agius, Soheil Sabri, Mohsen Kalantari   +2 more
doaj   +1 more source

Development of Cost and Schedule Data Integration Algorithm Based on Big Data Technology

Applied Sciences, 2020
In the information age, the role of data in any industry is getting more and more important. In the construction industry, however, experts’ experience and intuition are still key determinants in decision-making, while other industries achieve tangible ...
Daegu Cho, Myungdo Lee, Jihye Shin
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Spatial data infrastructure for ecological environment [PDF]

, 2013
The main objective is to ensure the sustainable development of Energy, requires the development of enterprise geographic information systems (GIS) for the modeling of energy systems. The corporate GIS in Ukraine will increase the energy efficiency of the
Kuznetsova, O.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

3D Cadastral Database Systems—A Systematic Literature Review

ISPRS International Journal of Geo-Information
Cadastral databases have been used for over 20 years, but most contain 2D data. The increasing presence of high-rise buildings with modern architecture complicates the process of determining property rights, restrictions, and responsibilities.
Javad Shahidinejad, Mohsen Kalantari, Abbas Rajabifard   +2 more
doaj   +1 more source

Data-driven Strategies for Affordable Housing: A Hybrid Genetic Algorithm-Machine Learning Optimization Model in the Melbourne Metropolitan Area [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The escalating rental crisis in Australia, rooted in demographic dynamics, a scarcity of lands suitable for development and the influence of interest rates and government subsidies, necessitates innovative solutions for housing affordability.
P. Jafary, P. Jafary, D. Shojaei, S. Pishgahi, A. Rajabifard, T. Ngo, T. Ngo   +6 more
doaj   +1 more source

Accuracy of areal interpolation methods for count data

, 2015
The combination of several socio-economic data bases originating from different administrative sources collected on several different partitions of a geographic zone of interest into administrative units induces the so called areal interpolation problem.
Do, Van Huyen, Thomas-Agnan, Christine, Vanhems, Anne   +2 more
core   +2 more sources

The Integration of Coastal Flooding into an ArcFLOOD Data Model [PDF]

, 2014
With the impact of global climate change, the speedy, intelligent and accessible dissemination of coastal flood predictions from a number of modelling tools at a range of temporal and spatial scales becomes increasingly important for policy decision ...
Nock, Alison Heidi
core   +2 more sources