Results 51 to 60 of about 13,846 (261)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Structural Analysis Ready Building Information Modelling: A Requirement Analysis [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Structural analysis is utilised to evaluate the behaviour of structures under applied loads to ensure their safety and stability. It is crucial in designing, assessing, and retrofitting buildings and structures.
M. Akhoundi Khezrabad, D. Shojaei, M. Tomko   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Three-Dimensional Rule-Based City Modelling to Support Urban Redevelopment Process

ISPRS International Journal of Geo-Information, 2018
Multi-dimensional representation of urban settings has received a great deal of attention among urban planners, policy makers, and urban scholars. This is due to the fact that cities grow vertically and new urbanism strategies encourage higher density ...
Tyler Agius, Soheil Sabri, Mohsen Kalantari   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Improving the Decision-Making for Sustainable Demolition Waste Management by Combining a Building Information Modelling-Based Life Cycle Sustainability Assessment Framework and Hybrid Multi-Criteria Decision-Aiding Approach

Recycling
Increasing efforts have been devoted to promoting sustainable demolition waste management (DWM) from a life cycle thinking perspective. To this end, facilitating sustainability-oriented decision-making for DWM planning requires a sustainability ...
Dongchen Han, Abbas Rajabifard
doaj   +1 more source

Data-driven Strategies for Affordable Housing: A Hybrid Genetic Algorithm-Machine Learning Optimization Model in the Melbourne Metropolitan Area [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The escalating rental crisis in Australia, rooted in demographic dynamics, a scarcity of lands suitable for development and the influence of interest rates and government subsidies, necessitates innovative solutions for housing affordability.
P. Jafary, P. Jafary, D. Shojaei, S. Pishgahi, A. Rajabifard, T. Ngo, T. Ngo   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Spatially Enabled society

Geoforum Perspektiv, 2012
The term ‘spatially enabled society’ describes the emerging cultural and governance revolution offered by pervasive spatial information technologies and spatially equipped citizens.
Stig Enemark, Abbas Rajabifard
doaj   +1 more source