Results 61 to 70 of about 1,084,982 (293)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Direction-Aware Nearest Neighbor Query
Although the direction aspect is as important as the distance aspect when retrieving spatial objects, the studies of direction-aware queries are limited. The direction-based surrounder query cannot guarantee good directional diversity.
Xi Guo, Xiaochun Yang
doaj +1 more source
Rapid urbanization has led vertical infrastructural growth in different countries with differing economic development levels and social systems. The two cities, Prague and Delhi, are the capital cities of their respective countries and have significant ...
Tarun Ghawana +2 more
doaj +1 more source
The Impact of Global Clustering on Spatial Database Systems [PDF]
Global clustering has rarely been investigated in the area of spatial database systems although dramatic performance improvements can be achieved by using suitable techniques.
Brinkhoff, Thomas, Kriegel, Hans-Peter
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Thematic Geovisualization of the Data Profile of Kaligesing, Purworejo, Central Java
The scientific field has a variety of purposes, one of which is the presentation of data and information which can be used by other parties to support their decision making. Moreover, the information is presented spatially.
Sudaryatno Sudaryatno +2 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Evaluation of Topological Consistency in CityGML
Boundary representation models are data models that represent the topology of a building or city model. This leads to an issue in combination with geometry, as the geometric model necessarily has an underlying topology.
Anna Giovanella +2 more
doaj +1 more source
The main objective of this work is to develop a methodology for analyzing the quality of the voltage level in the distribution power grid to identify and reduce the violations of voltage limits through the proposition of optimal points for the allocation
José A. G. Cararo +6 more
doaj +1 more source

