Results 71 to 80 of about 5,687,015 (319)
Query processing of spatial objects: Complexity versus Redundancy [PDF]
, 1993 The management of complex spatial objects in applications, such as geography and cartography, imposes stringent new requirements on spatial database systems, in particular on efficient query processing. As shown before, the performance of spatial query
A. Braun +9 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Energies, 2021 The main objective of this work is to develop a methodology for analyzing the quality of the voltage level in the distribution power grid to identify and reduce the violations of voltage limits through the proposition of optimal points for the allocation
José A. G. Cararo +6 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Enhancing Disaster Management: Development of a Spatial Database of Day Care Centers in the USA
ISPRS International Journal of Geo-Information, 2015 Children under the age of five constitute around 7% of the total U.S. population, and represent a segment of the population that is totally dependent on others for day-to-day activities.
Nagendra Singh +2 more
doaj +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Perancangan Data Warehouse dan Penerapan Teknik Clustering Spatial pada Wesel: Studi Kasus PT XXX
ComTech, 2013 By setting up the right service and product for the customer, the company may increase its marketing effectiveness as well as sales. For that purpose, information on company’s product and sales is highly needed in order to help on decision making ...
Arief Dwi Hartadi, Oktalia Juwita
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Building a Spatial Database by Developing a Work Environment to Accomplish the Automatic Transfer Process for Remote Sensing Data from Raster to Linear [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2010 In this paper a develop an working environment for building spatial database by utilizing ArcView Geographic Information System software package and IDRISI software package for remotely sensed images processing is obtained.
Diaa Al-Berhawi
doaj +1 more source