Spatial Dependence of Log-Transformed Electromyography-Force Relation: Model-Based Sensitivity Analysis and Experimental Study of Biceps Brachii. [PDF]
Huang C, Chen M, Lu Z, Klein CS, Zhou P.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Housing Risk and Returns in Submarkets with Spatial Dependence and Heterogeneity. [PDF]
Morawakage PS +4 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells. [PDF]
Tsuchiya T, Hori H, Ozaki H.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
TGN: A Temporal Graph Network for Physics Prediction
Long-term prediction of physical systems on irregular unstructured meshes is extremely challenging due to the spatial complexityof meshes and the dynamic changes over time; namely, spatial dependence and temporal dependence.
Miaocong Yue +4 more
doaj +1 more source
Nanoscale spatial dependence of avidity in an IgG1 antibody. [PDF]
Jendroszek A, Kjaergaard M.
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Examining Time-Variant Spatial Dependence of Urban Places and Shootings. [PDF]
Oliphant SN.
europepmc +1 more source

