Results 81 to 90 of about 217,536 (268)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
AnimalsThis study examined the socioeconomic and veterinary cost factors influencing dog abandonment and adoption outcomes across 162 regions in the Republic of Korea from 2021 to 2023.
HyungChul Rah
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
NONTESTABILITY OF EQUAL WEIGHTS SPATIAL DEPENDENCE [PDF]
Econometric Theory, 2011 We show that any invariant test for spatial autocorrelation in a spatial error or spatial lag model with equal weights matrix has power equal to size. This result holds under the assumption of an elliptical distribution. Under Gaussianity, we also show that any test whose power is larger than its size for at least one point in the parameter space must ...
openaire +4 more sources
A framework for modeling county-level COVID-19 transmission
Frontiers in Public HealthThis study examines COVID-19 transmission across 3,142 U.S. counties using a truncated dataset from March to September 2020. County-level factors include demographics, socioeconomic status, environmental conditions, and mobility patterns.
Yida Bao +6 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Frontiers in Sustainable Food SystemsDiversification has been practiced by several economies globally due to its potential to drive structural economic transformation as well as its prospects in reducing the risks associated with crop failure under monocrop production regimes.
Ebenezer Kondo +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e ZootecniaRESUMO O objetivo da realização deste trabalho foi analisar a variabilidade espacial da composição do leite cru refrigerado e elaborar mapas com interpolação de dados sobre os teores de gordura, proteína, lactose, sólidos totais e extrato seco ...
M.T. Férrer +3 more
doaj +1 more source
Bulletin of Geography. Socio-Economic Series, 2015 A great number of contemporary studies are incorporating explicit consideration of spatial effects in the estimation of hedonic price functions. At the most basic level, interactive spatial regime models are employed to detect the presence of spatial ...
Khalid Haniza
doaj +1 more source