Results 111 to 120 of about 1,155,613 (311)

Spatial distribution of malaria transmission in relationship to "Anopheles gambiae" complex members in Sudan savanna and irrigated rice cultivation areas of Mali [PDF]

open access: yes, 2007
Malaria remains a major public health problem that is exacerbated by poor implementation of control measures, and by the spread of drug-resistant parasites and insecticide resistant vectors. Preventive measures, including those targeted at vectors, are
Sogoba, Nafomon
core   +1 more source

Spatial distribution of leprosy in areas of risk in Vitoria, State of Espirito Santo, Brazil, 2005 to 2009

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction Leprosy remains a relevant public health issue in Brazil. The objective of this study was to analyze the spatial distribution of new cases of leprosy and to detect areas with higher risks of disease in the City of Vitória.
Poliane Barbosa Sampaio   +4 more
doaj   +1 more source

Spatial distribution of leprosy in Nigeria

open access: yesLeprosy Review, 2016
Despite achieving the WHO elimination target of less than 1/10,000 population in 1998 at the national level, there are still pockets of relative high endemicity of leprosy in Nigeria. This study used spatial analytic techniques to determine the spatial distribution of leprosy in Nigeria.The study is an ecological study of secondary data of new leprosy ...
Olusoji J, Daniel   +5 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Convergence in Mississippi: A Spatial Approach. [PDF]

open access: yes
Mississippi constitutes an interesting case study for analyzing the income convergence process because of several characteristics, such as the fairly large number of counties, its relative homogeneous economy and its low percapita income compared with ...
Mihai Nica
core  

Spatial Distribution of Poverty in Chile

open access: yesEstudios de Economía, 2016
Chile’s recent success in reducing poverty has been remarkable, with poverty rates falling by approximately two-thirds over the last 20 years. However, further gains against poverty may be inhibited by the increasing difficulty associated with ...
Claudio Agostini
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

"Stability of Spatial Equilibrium" [PDF]

open access: yes
This paper focuses on externalities between economic agents. We consider spatial dis- tribution of economic activities in a multiregional dynamical system, where regions may be interpreted as clubs, social subgroups, species, or strategies.
Takatoshi Tabuchi, Dao-Zhi Zeng
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

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