Results 61 to 70 of about 1,155,613 (311)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Spatially distributed cell signalling [PDF]
FEBS Letters, 2009 Emerging evidence indicates that complex spatial gradients and (micro)domains of signalling activities arise from distinct cellular localization of opposing enzymes, such as a kinase and phosphatase, in signal transduction cascades. Often, an interacting, active form of a target protein has a lower diffusivity than an inactive form, and this leads to ...
openaire +4 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Species spatial distribution analysis using nearest neighbor methods: aggregation and self-similarity [PDF]
, 2014 Spatial aggregation and self-similarity are two important properties in species spatial distribution analysis and modeling. The aggregation parameter k in the negative binomial distribution model and fractal dimension are two widely used measures of ...
Wang, Xinxiu +3 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Spatial variability of groundwater recharge - II. Factors affecting variability and taking account of it in estimating recharge [PDF]
, 2004 The accompanying paper provided evidence to suggest that spatial variability of groundwater recharge is ‘true’ variability. This paper attempts to determine the major causes of such variability even at small distances, if there appear to be a frequency ...
De Silva, RP
core
Spatial distribution of precipitation in Lithuania
Mokslas: Lietuvos Ateitis, 2011 Analysis is based on a 36-year record (1971–2006) of daily precipitation at 17 meteorological stations throughout Lithuania. The obtained data was used to investigate the spatial properties of the precipitation fields of monthly decadals (10-days).
Viktorija Grušaitė
doaj +1 more source
Spatially Distributed Normative Objects [PDF]
, 2007 Organisational structures for multi-agent systems are usually defined independently of any spatial or temporal structure. Therefore, when the multiagent system is situated in a spatial environment, there is usually a conceptual gap between the definition of the system’s organisational structures and the definition of the environment.
Fabio Y. Okuyama +2 more
openaire +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A short geostatistical study of the three-dimensional spatial structure of fumonisins in stored maize [PDF]
, 2010 The heterogeneous three-dimensional spatial distribution of mycotoxins has proven to be one of the main limitations for the design of effective sampling protocols.
N. Magan +12 more
core +1 more source