Results 61 to 70 of about 3,311,762 (298)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatial Distribution of Planktonic Dinoflagellate in Makassar Waters, South Sulawesi [PDF]

open access: yes, 2015
The objectives of this study were to determine the harmful species of dinoflagellates, to determine the concentration of nutriens in surface waters, and to analyze factors affecting the ecological aspects of the harmful dinoflagellates.
Damar, A. (Ario)   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Spatial distribution of stellar populations in the Magellanic Clouds: Implementation to Gaia

open access: yes, 2011
The main goal of our project is to investigate the spatial distribution of different stellar populations in the Magellanic Clouds. The results from modelling the Magellanic Clouds can be useful, among others, for simulations during the Gaia mission ...
Bekki   +28 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Spatial distribution of the attentional blink

open access: yesFrontiers in Psychology, 2011
In the present study subjects viewed streams of rapid serially presented characters and searched for a target digit. After presentation of the target digit, a second target consisting of an orientation singleton (Experiment 1) or a second digit ...
FENG eDU, Richard eAbrams, Kan eZhang
doaj   +1 more source

Spatial distribution of angular momentum inside the nucleon

open access: yes, 2017
We discuss in detail the spatial distribution of angular momentum inside the nucleon. We show that the discrepancies between different definitions originate from terms that integrate to zero.
Lorcé, Cédric   +2 more
core   +4 more sources

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