Results 81 to 90 of about 1,155,613 (311)

The regional distribution of spanish unemployment. A spatial analysis [PDF]

open access: yes
This paper proposes a set of tools to analyse the regional distribution of unemployment. As we are interested in the characteristics of the whole distribution, we complement results from the traditional regression analysis with those from the estimation ...
Artis, Manuel   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Extent and spatial distribution of karst in Slovenia [PDF]

open access: yes
A spatial database was created in the form of a polygon shape file (.shp) contains data on the occurrence of karst and the lithological type of karst for each of the 1:100,000 scale lithological polygons in Slovenia.
Stepišnik, Uroš, Gostinčar, Petra
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Spatial Distribution of Labour Force Participation and Market Earnings at the Sub-National Level in Ireland [PDF]

open access: yes
The main aim of this paper is to provide a spatial modelling framework for labour force participation and income estimation. The development of a household income distribution for Ireland had previously been hampered by the lack of disaggregated data on ...
Cathal O'Donoghue, Karyn Morrissey
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Asymptotic Distribution of the OLS Estimator for a Mixed Regressive, Spatial Autoregressive Model [PDF]

open access: yes
We find the asymptotics of the OLS estimator of the parameters $\beta$ and $\rho$ in the spatial autoregressive model with exogenous regressors $Y_n = X_n\beta+\rho W_nY_n+V_n$. Only low-level conditions are imposed.
Mynbaev, Kairat
core   +1 more source

Spatial Ecology of Aedes Albopictus in Suburban Landscapes of a Piedmont Community in North Carolina [PDF]

open access: yes, 2005
The objectives of our study were to investigate the spatial ecology of Ae. albopictus, to evaluate some potential management methods, and to characterize its host feeding patterns in a suburban landscape. We monitored Ae. albopictus oviposition activity
Richards, Stephanie Lynn
core  

Mapeando a fecundidade nordestina: 2000-2010

open access: yesConfins, 2017
The results of the 2010 Demographic Census show that, among the three most populous Brazilian regions (representing more than 80% of the Brazilian population), the Northeast was the region registering the highest rate of population growth between 2000 ...
Morvan de Mello Moreira, Wilson Fusco
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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