Results 131 to 140 of about 6,256 (263)

Multimodal Super‐Resolution Imaging of Nitrogen‐Vacancy Centers via High‐Index‐Induced Structured Illumination Microscopy and Optically Detected Magnetic Resonance Spectrometry

open access: yesAdvanced Science, EarlyView.
This work demonstrates a multimodal super‐resolution imaging technique for nitrogen‐vacancy centers by integrating high‐index‐induced structured illumination with optically detected magnetic resonance. By utilizing diamond's high refractive index, the method achieves sub‐100‐nm spatial resolution and enhanced localization. This dual‐modulation strategy
Kyu Ri Choi   +9 more
wiley   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke   +14 more
wiley   +1 more source

Ultra-wideband optical diffractive network for mode multiplexing across the entire telecommunication range. [PDF]

open access: yesNat Commun
Kong A   +13 more
europepmc   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

open access: yesAdvanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed   +10 more
wiley   +1 more source

Realization of a Bilayer Elastic Topological Insulator

open access: yesAdvanced Science, EarlyView.
Bilayer elastic wave topological insulators are experimentally realized, introducing the layer degree of freedom to access four topological phases. This enables diverse domain walls and transmission behaviors, including interlayer conversion and beam splitting.
Chengzhi Ma   +4 more
wiley   +1 more source

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