Results 121 to 130 of about 2,853,438 (289)

A Decision Support System Platform for Spatial Epidemiology

, 2015
A wide range of health care systems have been implemented, to support medical opinions, which are defined as Decision Support Systems. In this work a pilot information system was developed based on patients health records data combined with Geographical Information Systems (GIS) technology, which could be used as an advisor in cases where ...
Stelios Zimeras, Aggelos Mechili, Marianna Diomidous   +2 more
openaire   +4 more sources

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

Advanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin, Shengjia Ye, Yun Yuan, Xueying Yang, Jiarui Cui, Hongming Zhang, Hui Huang   +6 more
wiley   +1 more source

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

Spatial lifecourse epidemiology [PDF]

The Lancet Planetary Health, 2019
openaire   +3 more sources

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Social Epidemiology

, 2014
Social epidemiology has been defined as the branch of epidemiology that studies the social distribution and social determinants of health (Berkman and Kawachi 2000).
Chandola, Tarani, Kumari, Meena, Marmot, Michael, Tarani Chandola, Meena Kumari, Michael Marmot   +5 more
core   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source

Spatiotemporal pattern and suitable areas analysis of equine influenza in global scale (2005–2022)

Frontiers in Veterinary Science
Equine influenza (EI) is a severe infectious disease that causes huge economic losses to the horse industry. Spatial epidemiology technology can explore the spatiotemporal distribution characteristics and occurrence risks of infectious diseases, it has ...
Jiafeng Ding, Jiafeng Ding, Jiafeng Ding, Yu Wang, Yu Wang, Jinjiao Liang, Jinjiao Liang, Zhenhuan He, Changhong Zhai, Changhong Zhai, Yinghao He, Yinghao He, Jiayin Xu, Jiayin Xu, Lei Lei, Lei Lei, Jing Mu, Jing Mu, Min Zheng, Boyang Liu, Mingxian Shi, Mingxian Shi   +21 more
doaj   +1 more source

Review of geo-spatial sampling methods for parasite ecology and epidemiology studies

, 2013
geo-spatial sampling methods to study epidemiology of ...
Lagazio C., Hendrichx G., RINALDI, LAURA, Mintiens K., Biggeri A., Ducheyne E., Musella V., CRINGOLI, GIUSEPPE, Catelan D.   +8 more
core  

MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation‐Associated Colorectal Cancer by Suppressing the STAT3‐CCL2 Axis and TAM‐Mediated Immunosuppression

Advanced Science, EarlyView.
Our study identifies MAGI3 as an intestinal epithelial gatekeeper that restrains inflammation‐associated colorectal tumorigenesis but is itself suppressed under highly inflammatory conditions. MAGI3 deficiency activates the STAT3‐CCL2 signaling, thereby promoting TAM‐mediated immunosuppression and inflammation‐associated colorectal tumor progression ...
Yumeng Yang, Zhigang Bai, Haibo Wang, Yu Guo, Yan Zhang, Meihan Hu, Shuaikang Fan, Ran Song, Tongmei Zhang, Mengqi Deng, Xiaomei Yang, Zhongtao Zhang, Junqi He   +12 more
wiley   +1 more source