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Spatial Transcriptomics for Tumor Heterogeneity Analysis
The molecular heterogeneity of cancer is one of the major causes of drug resistance that leads to treatment failure. Thus, better understanding the heterogeneity of cancer will contribute to more precise diagnosis and improved patient outcomes.
Rongqin Ke
exaly +3 more sources
Spatial heterogeneity represents a general characteristic of the inequitable distributions of spatial issues. The spatial stratified heterogeneity analysis investigates the heterogeneity among various strata of explanatory variables by comparing the ...
Yong Ge, Jinfeng Wang, Chengdong Xu
exaly +2 more sources
Spatial protein heterogeneity analysis in frozen tissues to evaluate tumor heterogeneity
A new workflow for protein-based tumor heterogeneity probing in tissues is here presented. Tumor heterogeneity is believed to be key for therapy failure and differences in prognosis in cancer patients. Comprehending tumor heterogeneity, especially at the
Anna Fomitcheva-Khartchenko +4 more
doaj +2 more sources
Modeling of spatial stratified heterogeneity
Spatial stratified heterogeneity (SSH) refers to the geographical phenomena in which the geographical attributes within-strata are more similar than the between-strata, which is ubiquitous in the real world and offers information implying the causation ...
Jiangang Guo +3 more
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Geospatial phenomena often have spatial heterogeneity, which is caused by differences in the data generation process from place to place. There are two types of spatial heterogeneity: continuous and discrete, and there has been much discussion about how ...
Ryo Inoue, Koichiro Den
doaj +1 more source
The Spatial Effects of Regional Poverty: Spatial Dependence, Spatial Heterogeneity and Scale Effects
Recognizing the spatial effects of regional poverty is essential for achieving sustainable poverty alleviation. This study investigates these spatial effects and their determinants across three distinct administrative levels within Hubei Province, China.
Mengxiao Liu +3 more
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Spatial heterogeneity of the shorebird gastrointestinal microbiome [PDF]
The gastrointestinal tract (GIT) consists of connected structures that vary in function and physiology, and different GIT sections potentially provide different habitats for microorganisms.
Kirsten Grond +2 more
doaj +1 more source
A Lacunarity‐Based Index for Spatial Heterogeneity
Characterizing spatial heterogeneity is fundamental in numerous areas, yet defining spatial patterns often depends on qualitative assessments or a priori knowledge.
R. Scott +4 more
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Spatial heterogeneity in plant communities promotes coexistence and diversity by providing a variety of niches for different species. In shrub-steppe communities, shrubs create distinct microsites under their canopies (canopy microsites) compared to ...
Kirk W. Davies +2 more
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Soil heterogeneity has been shown to enhance plant diversity, but its effect on grassland productivity is less clear. Even less is known about the effect of plant clumping (intraspecific aggregation) and its potential interaction with soil heterogeneity.
O. Vindušková +5 more
doaj +1 more source

