Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Nonlinear drivers and spatial heterogeneity of urban heat islands in lake-dense regions across ecological stress-structure-service interactions. [PDF]
Xiong S, Yang F, Fan H.
europepmc +1 more source
The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci +25 more
wiley +1 more source
Spatial heterogeneity determines the gastrointestinal microbiome signatures in Pekin ducks. [PDF]
Zhao H +8 more
europepmc +1 more source
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah +4 more
wiley +1 more source
Spatial heterogeneity of the microbiota in <i>Cypripedium franchetii</i> and Its correlation with organ-specific metabolomes. [PDF]
Tang Y +5 more
europepmc +1 more source
Interstitial lung disease (IRD‐ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRD). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the non‐invasive assessment of ILD; however, its interpretation is constrained by substantial inter‐observer variability and ...
Alexander Pfeil +7 more
wiley +1 more source
Spatial heterogeneity, trade-offs, and bundle identification of ecosystem services in karst watersheds: a comprehensive assessment of the Lijiang River Basin. [PDF]
Feng Y, Huang Y, Wu Z, Sun R, Wang Y.
europepmc +1 more source
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar +2 more
wiley +1 more source
Structure and Spatial Heterogeneity of Chemosynthesis-Based Deep-Sea Archaeal and Bacterial Communities in Western South Atlantic. [PDF]
Lopes Simão TL +11 more
europepmc +1 more source

