Results 91 to 100 of about 18,308,463 (305)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

09161 Abstracts Collection – Generalization of spatial information [PDF]

, 2009
From 13.04. to 17.04.2009, the Dagstuhl Seminar 09161 ``Generalization of spatial information '' was held in Schloss Dagstuhl~--~Leibniz Center for Informatics. During the seminar, several participants presented their current research, and ongoing work
van Harmelen, Frank, Mustière, Sébastien, Sester, Monika, van Oosterom, Peter   +3 more
core   +1 more source

A Texture-Considerate Convolutional Neural Network Approach for Color Consistency in Remote Sensing Imagery

Remote Sensing
Remote sensing allows us to conduct large-scale scientific studies that require extensive mapping and the amalgamation of numerous images. However, owing to variations in radiation, atmospheric conditions, sensor perspectives, and land cover, significant
Xiaoyuan Qian, Cheng Su, Shirou Wang, Zeyu Xu, Xiaocan Zhang   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Hydrological Analysis Using Satellite Remote Sensing Big Data and CREST Model

IEEE Access, 2018
Hydrological modeling significantly contributes to the understanding of catchment water balance and water resource management and mitigates negative impacts of flooding.
Jun Ma, Weiwei Sun, Gang Yang, Dianfa Zhang   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Assessing Spatial Information in Physical Environments (Short Paper)

, 2019
Many approaches have dealt with the hypothesis that the environment contain information, mostly focusing on how humans decode information from the environment in visual perception, navigation, and spatial decision-making.
Cacholas, Caio, Netto, Vinicius M., Aleixo, Vinicius Gomes, Brigatti, Edgardo   +3 more
core   +1 more source

Virtual 3D City Model Generation in CityGML [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
As the urban digital transformation continues to advance, virtual 3D city models have become essential tools for urban planning, traffic management, environmental assessment, and virtual reality applications.
C. Zhao, Y. Ogawa, L. Liao, Y. Sekimoto
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source