Results 101 to 110 of about 18,308,463 (305)
Islands are sensitive zones of sea-land interaction and typical ecologically fragile areas that are highly vulnerable to natural disasters, especially marine aquaculture, which is sensitive and at high risk to typhoon disasters; additionally, they are ...
Wang Yu +4 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Intuitive Modelling of Place Name Regions for Spatial Information Retrieval
Reasoning about spatial relevance is important for intelligent spatial information retrieval. In heterogeneous and distributed systems like the Semantic Web, spatial reasoning has to be based on light-weight, interoperable and easy-to-use spatial ...
Schlieder, Christoph +2 more
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Predicting Building Height from Footprint and Urban Planning information for Digital Twin Generation [PDF]
Accurate building height data is essential for constructing realistic and analytically useful 3D city models within digital twin systems. However, such data are often incomplete, particularly in small to medium-sized cities. This study presents a machine
J. Ma, C. Zhao, Y. Ogawa, Y. Sekimoto
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Parts-per-quadrillion level gas molecule detection: CO-LITES sensing
Highly sensitive gas detection plays a crucial role in advanced scientific and technological fields. This paper presents a parts-per-quadrillion (ppq) level ultra-highly sensitive light-induced thermoelectric spectroscopy (LITES) sensor for the first ...
Haiyue Sun +4 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source

