Results 121 to 130 of about 18,308,463 (305)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Classifying and Utilizing the Geo-Spatial Information in Smart City

open access: yes, 2009
It has been difficult to locate necessary information quickly in a complicated geo-spatial information network. Textual and numerical information is disadvantageous in that viewers may not have cognitive power and thus do not understand it properly ...
J. Choi, M. Kim
core  

Construction of dynamic trafficability map for unmanned vehicles considering multiple environmental factors and path planning

open access: yesScientific Reports
Comprehensively considering the off-road trafficability of multiple environmental factors and carrying out optimal path planning is very important for assisting commanders to formulate battlefield maneuvering plans.
Qingyun Liu   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Spatial Information Retrieval with Place Names [PDF]

open access: yes, 2004
This work outlines an approach to handle the spatial dimension of information retrieval, i.e. queries of the type concept @ location. It applies a low-level notion of spatial relevance that is closely linked to the location, or geo-reference, of an ...
Vögele, Jörg-Thomas
core  

Reasoning over Spatial Orientation Relations Using Rules [PDF]

open access: yes
Representation of spatial information for the Semantic Web often involves qualitative defined information (i.e., information described using natural language terms such as "Left"), since precise arithmetic descriptions using coordinates and angles are
Tachmazidis, Ilias   +2 more
core   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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