Results 31 to 40 of about 2,481,877 (286)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

PoD: A Web Tool for Population Downscaling Using Areal Interpolation and Volunteered Geographic Information

open access: yesEuropean Journal of Geography, 2023
Population data are commonly sourced from censuses, and to meet confidentiality requirements, they are spatially aggregated into standardized enumeration units.
Marios Batsaris   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Comparison Between Deterministic and Stochastic Interpolation Methods for Predicting Ground Water Level in Baghdad [PDF]

open access: yesEngineering and Technology Journal, 2018
Surface interpolation techniques are usually used to create continuous data (i.e. raster data) from distributed set of point data over a geographical region.
Muammar Ali   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A disposition of interpolation techniques [PDF]

open access: yes, 2010
A large collection of interpolation techniques is available for application in environmental research. To help environmental scientists in choosing an appropriate technique a disposition is made, based on 1) applicability in space, time and space-time, 2)
Heuvelink, G.B.M., Knotters, M.
core  

Research for Interpolation Method of Spatial Variation Analysis on Soil Salinity in the Oasis

open access: yesShuitu baochi yanjiu, 2014
In order to compare the advantages and disadvantages of the spatial interpolation methods of the soil salinity spatial variation,a case study of Weiku,Oasis using four spatial interpolation methods based on ArcGIS(inverse distance weighting,spline ...
MA Cheng-xia   +5 more
doaj  

A comprehensive assessment of spatial interpolation methods for the groundwater quality evaluation of Lahore, Punjab, Pakistan

open access: yesNUST Journal of Engineering Sciences, 2017
Spatial interpolation is commonly used to generate water quality surfaces, but different spatial interpolation methods yield different surfaces from the same data.
Syed Umair Shahid   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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