Results 41 to 50 of about 86,327 (302)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Distance in spatial interpolation of daily rain gauge data [PDF]
Hydrology and Earth System Sciences, 2006 Spatial interpolation of rain gauge data is important in forcing of hydrological simulations or evaluation of weather predictions, for example. This paper investigates the application of statistical distance, like one minus common variance of observation
B. Ahrens, B. Ahrens
doaj
Application of a four-dimensional space fractal interpolation algorithm in grade estimation
工程科学学报, 2015 Kriging interpolation is a widely used low-pass filter interpolation method, but it cannot reconstruct the high-frequency, low-frequency and partial information of original information.
HU Nai-lian +3 more
doaj +1 more source
Agriculture, 2023 Soil fertility plays a crucial role in crop growth, so it is important to study the spatial distribution and variation of soil fertility for agricultural management and decision-making.
Wenhui Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A disposition of interpolation techniques [PDF]
, 2010 A large collection of interpolation techniques is available for application in environmental research. To help environmental scientists in choosing an appropriate technique a disposition is made, based on 1) applicability in space, time and space-time, 2)
Heuvelink, G.B.M., Knotters, M.
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Estimation of missing rainfall data in northeast region of Thailand using spatial interpolation methods [PDF]
, 2011 Ground-based rainfall observations are the primary sources of precipitation data used in most developing countries. However, those observations are frequently damaged or incomplete, thus missing data is always a problem.
Wong, K.W., Fung, C.C., Kajornrit, J.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source