Results 71 to 80 of about 2,481,877 (286)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

A FAST MORPHING-BASED INTERPOLATION FOR MEDICAL IMAGES: APPLICATION TO CONFORMAL RADIOTHERAPY

Image Analysis and Stereology, 2011
A method is presented for fast interpolation between medical images. The method is intended for both slice and projective interpolation. It allows offline interpolation between neighboring slices in tomographic data.
Hussein Atoui, Serge Miguet, David Sarrut   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Application of Empirical Orthogonal Function Interpolation to Reconstruct Hourly Fine Particulate Matter Concentration Data in Tianjin, China

Complexity, 2020
Fine particulate matter with diameters less than 2.5 μm (PM2.5) concentration monitoring is closely related to public health, outdoor activities, environmental protection, and other fields.
Hongwu Zhou, Haidong Pan, Shuang Li, Xianqing Lv   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Wind resource mapping using landscape roughness and spatial interpolation methods [PDF]

, 2015
Energy saving, reduction of greenhouse gasses and increased use of renewables are key policies to achieve the European 2020 targets. In particular, distributed renewable energy sources, integrated with spatial planning, require novel methods to optimise ...
Samuel Van Ackere, Karel Van Wyngene, Papa, Enrica, van Acker, S., Van Wyngene, K., Vandevelde, L., David Schillebeeckx, Vandevelde, Lieven, Greet Van Eetvelde, Van Ackere, Samuel, Schillebeeckx, David, Van Eetvelde, Greet, Enrica Papa, Papa, E., Van Eetvelde, G., Lieven Vandevelde, Van Wyngene, Karel   +16 more
core   +1 more source

Benchmarking Knowledge-assisted Kriging for Automated Spatial Interpolation of Wind Measurements

- We have benchmarked a novel knowledge-assisted kriging algorithm that allows regions of spatial cohesion to be specified and variograms calculated for each region.
Zlatev, Zlatko, Middleton, Stuart, Veres, Galina   +2 more
core   +1 more source

Study on Spatial Variability of Available Nitrogen in Different Sampling Scale——A Case Study on Cropland Soil in Yushu City

Shuitu baochi yanjiu, 2012
During the implementation of precision agriculture,it is a key issue to search for how to use the fewer samples to reflect the spatial variability of the field of information,and then use the scientific method of interpolation and the interpolation to ...
LIU Ji-ping, LIU Jia-xin, YU Yang, TIAN Xue-zhi, XU Yan-yan   +4 more
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

SPATIAL CHOW-LIN METHODS: BAYESIAN AND ML FORECAST COMPARISONS [PDF]

Completing data that are collected in disaggregated and heterogeneous spatial units is a quite frequent problem in spatial analyses of regional data.
Richard Sellner, Wolfgang Polasek
core