Results 71 to 80 of about 376,997 (285)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
, 2018 We present an effective harmonic density interpolation method for the numerical evaluation of singular and nearly singular Laplace boundary integral operators and layer potentials in two and three spatial dimensions. The method relies on the use of Green'
Faria, Luiz M. +2 more
core +3 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Spatial interpolation of dry deposition using EOF models
Revista de Matemática: Teoría y Aplicaciones, 2009 Random processes are monitored over space and time by a network of stations distributed across a spatial region. Auxiliary information is often gathered not only at the stations but at other points across the region.
Breda Muñoz Hernández
doaj +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
ProceedingsThe comfort level of air temperature in a region is one of the influencing factors that affect tourists’ choice of tourism purpose. As a national red cultural mecca, the study of air temperature in Jiangxi Province can provide an important scientific ...
Zihao Feng +4 more
doaj +1 more source
GRID2D/3D: A computer program for generating grid systems in complex-shaped two- and three-dimensional spatial domains. Part 1: Theory and method [PDF]
An efficient computer program, called GRID2D/3D was developed to generate single and composite grid systems within geometrically complex two- and three-dimensional (2- and 3-D) spatial domains that can deform with time.
Bailey, R. T. +3 more
core +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Biotechnologie, Agronomie, Société et Environnement, 2013 Watershed management and hydrological modeling require data related to the very important matter of precipitation, often measured using raingages or weather stations.
Ly, S., Charles, C., Degré, A.
doaj
Uncertainty Assessment for Management of Soil Contaminants with Sparse Data [PDF]
, 2018 In order for soil resources to be sustainably managed, it is necessary to have reliable, valid data on the spatial distribution of their environmental impact.
Schnabel, Ute +2 more
core