Results 111 to 120 of about 2,234,141 (283)

Agglomeration economies and the location of new information and communication technology (ICT) firms in the Netherlands [PDF]

open access: yes
In 2000, the world wide, rapid employment growth in the ICT-sector came to an end. Knowledge-intensive ICT-firms and -sectors in the Netherlands confirmed to this negative development trend as well. The life-cycle of the ICT-sector appears to reach a new
Atzema, Oedzge, van Oort, Frank
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

The Importance of Broadband Provision to Knowledge Intensive Firm Location [PDF]

open access: yes
Despite the volume of literature afforded knowledge work and innovations in information and communications technologies (ICTs), few studies have examined the importance of ICTs to firms in knowledge industries. This study will develop spatial econometric
Elizabeth A. Mack   +2 more
core  

Epistemologies of Spaces and Places: An Introduction [PDF]

open access: yes, 2014
The article introduces a special themed issue of Theory of Science on epistemologies of spaces and places. It provides a disciplinary context of the theme and reviews some of the key arguments that led to the so-called spatial turn in social sciences and
Hladík, Radim
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Spatial knowledge acquired from first-person and dynamic map perspectives. [PDF]

open access: yesPsychol Res, 2021
van der Kuil MNA   +3 more
europepmc   +1 more source

Economic Debate On Spatial Functional Linkages And Its Application to Key Spatial Development Challanges In Poland [PDF]

open access: yes
This article presents a synthesis of today's world economic knowledge and the results of the analyses concerning: a) the nature of spatial functional linkages, including network structures, b) diversity of approaches concerning the application of spatial
Jacek Zaucha
core  

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

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