Results 41 to 50 of about 9,962,303 (296)

Research on Parallel ISODATA Clustering for Remote Sensing Image Based on OpenMP [PDF]

open access: yesJisuanji gongcheng, 2016
The traditional image classification algorithm suffers from low efficiency and is unable to meet the requirement of mass and real-time processing of high resolution remote sensing data.Based on the analysis and research of the Iterative Self-organizing ...
LIU Yang,WANG Peng,YANG Rui,ZUO Xianyu,ZHANG Zhouwei,WU Xiaoyang,QU Jiantao
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

CHARACTERIZATION AND MODELING SURFACE SOIL PHYSICOCHEMICAL PROPERTIES USING LANDSAT IMAGES: A CASE STUDY IN THE IRAQI KURDISTAN REGION [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Quickly and accurately soil properties characterization is critical for many environmental and agricultural activities. This paper aimed at characterizing and modelling the surface soil physicochemical properties using soil laboratory analyses, Landsat-7
A. M. F. Al-Quraishi   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Spatial and temporal knowledge representation [PDF]

open access: yesEarth Science Informatics, 2009
Knowledge Representation (KR) originated as a discipline within Artificial Intelligence, and is concerned with the representation of knowledge in symbolic form so that it can be stored and manipulated on a computer. This article surveys that part of KR that is concerned with the representation of space and time, with particular reference to the use of ...
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Using the Spatial Knowledge of Map Users to Personalize City Maps: A Case Study with Tourists in Madrid, Spain

open access: yesISPRS International Journal of Geo-Information, 2018
The aim of personalized maps is to help individual users to read maps and focus on the most task-relevant information. Several approaches have been suggested to develop personalized maps for cities, but few consider the spatial knowledge of its users. We
María-Teresa Manrique-Sancho   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

An Investigation in Efficient Spatial Patterns Mining [PDF]

open access: yes
The technical progress in computerized spatial data acquisition and storage results in the growth of vast spatial databases. Faced with large amounts of increasing spatial data, a terminal user has more difficulty in understanding them without the ...
Wang, Lizhen
core   +4 more sources

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