Results 81 to 90 of about 2,238,587 (282)
A Spatial Analysis Of The Knowledge - Based Economy In Poland [PDF]
, 2014 The purpose of this article is to identify disparities in the use of knowledge in socio-economic life in the Polish provinces. The study was conducted using a taxonomic measure of development (one of the tools of multidimensional comparative analysis ...
Strożek, Piotr
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
KBGIS-2: A knowledge-based geographic information system [PDF]
The architecture and working of a recently implemented knowledge-based geographic information system (KBGIS-2) that was designed to satisfy several general criteria for the geographic information system are described.
Agarwal, P. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
How inter-firm networks influence the development of agglomerations [PDF]
, 2007 Non-market interactions are increasingly regarded as key explanations for spatial concentration. Consistently, both innovation and local knowledge spillovers play a central role in recent theories of agglomeration.
Boshuizen, Johannes, Veen, Anne van der
core +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Social Sciences, 2014 Climate change is globally defined as a “reality”. This does not mean however that the way in which it is understood is the same all over the world.
Gabriela B. Christmann +2 more
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Using a picture (or a thousand words) for supporting spatial knowledge of a complex virtual environment. [PDF]
Cogn Res Princ Implic, 2023 Jaeger AJ +3 more
europepmc +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source