Results 51 to 60 of about 4,258,489 (302)

Stroboscopic light stimulation as a controllable probe of the psilocybin state: a mechanistic framework and a falsifiable prediction

open access: yesFrontiers in Pharmacology
Stroboscopic light stimulation (SLS) and psilocybin each induce altered states whose phenomenology and neurophysiology partly overlap, including posterior alpha-band changes and visual imagery.
Kacper Żełabowski   +2 more
doaj   +1 more source

Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze

open access: yesMolecular Brain, 2011
Background Memory retrieval is not a passive process. Recent studies have shown that reactivated memory is destabilized and then restabilized through gene expression-dependent reconsolidation. Molecular studies on the regulation of memory stability after
Kim Ryang, Moki Ryouichi, Kida Satoshi
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Spatial navigation impairments among intellectually high-functioning adults with autism spectrum disorder: Exploring relations with theory of mind, episodic memory, and episodic future thinking [PDF]

open access: yes, 2013
Research suggests that spatial navigation relies on the same neural network as episodic memory, episodic future thinking, and theory of mind (ToM).
Lind, Sophie E.   +9 more
core   +1 more source

A consistent map in the medial entorhinal cortex supports spatial memory

open access: yesNature Communications
The medial entorhinal cortex (MEC) is hypothesized to function as a cognitive map for memory-guided navigation. How this map develops during learning and influences memory remains unclear. By imaging MEC calcium dynamics while mice successfully learned a
Taylor J. Malone   +12 more
doaj   +1 more source

Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits

open access: yesScientific Reports, 2022
Spatial disorientation is one of the earliest symptoms in Alzheimer’s disease and allocentric deficits can already be detected in the asymptomatic preclinical stages of the disease.
Nadine Curdt   +9 more
doaj   +1 more source

Social influences on spatial memory [PDF]

open access: yesMemory & Cognition, 2008
Three experiments were performed to examine the joint influences of spatial and social categories on memory for maps. Participants learned a map and descriptive information about small town businesses and, afterward, completed distance estimation and person-location matching tasks. Experiments 1 and 2 demonstrated that social (i.e., racial) and spatial
Keith B, Maddox   +3 more
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Working memory in children with developmental disorders [PDF]

open access: yes, 2009
The aim of the present study was to directly compare working memory skills across students with different developmental disorders to investigate whether the uniqueness of their diagnosis would impact memory skills.
Tracy, Alloway   +6 more
core   +1 more source

Emotional faces, visuo-spatial working memory and anxiety [PDF]

open access: yes, 2020
Recent research has demonstrated competition for limited cognitive resources, via emotional prioritization, occurs not only during attentional capture, but also extends to visuo-spatial working memory (VSWM).
Simione, Luca   +2 more
core   +1 more source

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