Results 131 to 140 of about 27,601,135 (361)

Selection of multi-model ensemble of general circulation models for the simulation of precipitation and maximum and minimum temperature based on spatial assessment metrics

open access: yes, 2019
. The climate modelling community has trialled a large number of metrics for evaluating the temporal performance of general circulation models (GCMs), while very little attention has been given to the assessment of their spatial performance, which is ...
K. Ahmed   +4 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

PERUBAHAN SPASIAL TUTUPAN LAHAN DI DAS CITARUM HULU

open access: yesJournal of Natural Resources and Environmental Management, 2018
Land cover is one of factors which is important in watershed management. The changes of land cover in a watershed can affect the hydrology abstraction. Land cover of upstream Citarum watershed is potentially changes.
Sri Malahayati Yusuf
doaj   +1 more source

An Anisotropic Model for Spatial Processes [PDF]

open access: yesGeographical Analysis, 2007
One of the key assumptions in spatial econometric modeling is that the spatial process is isotropic, which means that direction is irrelevant in the specification of the spatial structure. On the one hand, this assumption largely reduces the complexity of the spatial models and facilitates estimation and interpretation; on the other hand, it appears ...
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Spatial model of Dengue Hemorrhagic Fever (DHF) risk: scoping review. [PDF]

open access: yesBMC Public Health, 2023
Pakaya R   +3 more
europepmc   +1 more source

Testing for Simplification in Spatial Models [PDF]

open access: yes, 2002
Data collected on a rectangular lattice occur frequently in many areas such as field trials, geostatistics, remotely sensed data, and image analysis. Models for the spatial process often make simplifying assumptions, including axial symmetry and separability.
SCACCIA, LUISA, MARTIN R. J.
openaire   +1 more source

Spatial clustering method for geographic data

open access: yes, 2002
In the process of visualizing quantitative spatial data, it is necessary to classify attribute values into some class divisions. In a previous paper, the author proposed a classification method for minimizing the loss of information contained in ...
Osaragi, Toshihiro
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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