A SPATIAL MODEL OF REGIONAL VARIATIONS IN EMPLOYMENT GROWTH IN APPALACHIA [PDF]
In this study, a spatial equilibrium model of employment growth is developed and empirically estimated by Generalized Spatial Two-Stage Least Squares (GS2SLS) estimator using cross-sectional data from Appalachian counties for 1990-2000.
Peter V. SCHAEFFER +4 more
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
A Smart Spatial Routing and Accessibility Analysis System for EMS Using Catchment Areas of Voronoi Spatial Model and Time-Based Dijkstra's Routing Algorithm. [PDF]
Int J Environ Res Public Health, 2023 Alamri A.
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Spatial Modeling of Auto Insurance Loss Metrics to Uncover Impact of COVID-19 Pandemic
MathematicsThis study addresses key challenges in auto insurance territory risk analysis by examining the complexities of spatial loss data and the evolving landscape of territorial risks before and during the COVID-19 pandemic.
Shengkun Xie, Jin Zhang
doaj +1 more source
A spatial model to jointly analyze self-reported survey data of COVID-19 symptoms and official COVID-19 incidence data. [PDF]
Biom J, 2023 Vranckx M +9 more
europepmc +1 more source
Spatial Structures and Spatial Spillovers: A GME Approach [PDF]
Spatial econometrics is a subdiscipline that have gained a huge popularity in the last twenty years, not only in theoretical econometrics but in empirical studies as well. Basically, spatial econometric methods measure spatial interaction and incorporate
Esteban Fernandez Vazquez +2 more
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Morphology-dependent resonance enhanced nonlinear photoacoustic effect in nanoparticle suspension: a temporal-spatial model. [PDF]
Biomed Opt Express, 2021 Zheng Z +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source